γ-Aminobutyric acid hydrochloride supported on superparamagnetic γ-Fe2O3@SiO2 as a novel heterogeneous nanocatalyst for the synthesis of 2-amino-5-alkylidene-thiazol-4-one derivatives

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作者
Hadi Mohammadi
Hamid Reza Shaterian
机构
[1] University of Sistan and Baluchestan,Department of Chemistry, Faculty of Sciences
关键词
Nano-γ-Fe; O; @SiO; @[CH; ); -(γ-aminobutyric acid.HCl)]; Superparamagnetic nanocatalyst; 2-Amino-5-alkylidene-thiazol-4-ones; Three-component reaction,; Green reaction;
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学科分类号
摘要
γ-Aminobutyric acid hydrochloride immobilized on superparamagnetic γ-Fe2O3@SiO2 nanoparticles as a novel heterogeneous nanocatalyst was prepared for the first times. It was characterized by several techniques such as XRD, FT-IR, VSM, FE-SEM, EDS, and TGA analysis. The heterogeneous nanocatalyst was used for a convenient, mild, and one-pot efficient three-component preparation of 2-amino-5-alkylidene-thiazol-4-one derivatives under green conditions at room temperature. The main advantage of the method is easily recovery of the stable nanocatalyst by an external magnet from the reaction mixture.
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页码:479 / 492
页数:13
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