Efficient copper(I)-catalyzed, microwave-assisted, one-pot synthesis of 3,4-diaryl isoquinolines

被引：0
|
作者：
Zhang Hu
Li-Li Ou
Si-Dong Li
Lei Yang
机构：
[1] Guangdong Ocean University,Department of Chemistry, College of Science
[2] Zhejiang University,College of Pharmaceutical Science
来源：
Research on Chemical Intermediates | 2015年 / 41卷
关键词：
Isoquinolines; Copper-catalyzed; One-pot synthesis; Microwave irradiation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
An efficient copper-catalyzed, microwave-assisted, one-pot reaction has been developed for synthesis of 3,4-diaryl isoquinolines. The reaction was performed in two steps via a CuI/2,2′-biimidazole-catalyzed tandem process from N-tert-butyl-o-iodobenzaldimine and a terminal aryl alkyne, followed by addition of an aryl iodide. A variety of 3,4-diaryl isoquinolines have been obtained in moderate to good yields.
引用
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页码：3461 / 3469
页数：8
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