Efficient copper(I)-catalyzed, microwave-assisted, one-pot synthesis of 3,4-diaryl isoquinolines

被引：0

作者：

Zhang Hu

Li-Li Ou

Si-Dong Li

Lei Yang

机构：

[1] Guangdong Ocean University,Department of Chemistry, College of Science

[2] Zhejiang University,College of Pharmaceutical Science

来源：

Research on Chemical Intermediates | 2015年 / 41卷

关键词：

Isoquinolines; Copper-catalyzed; One-pot synthesis; Microwave irradiation;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

An efficient copper-catalyzed, microwave-assisted, one-pot reaction has been developed for synthesis of 3,4-diaryl isoquinolines. The reaction was performed in two steps via a CuI/2,2′-biimidazole-catalyzed tandem process from N-tert-butyl-o-iodobenzaldimine and a terminal aryl alkyne, followed by addition of an aryl iodide. A variety of 3,4-diaryl isoquinolines have been obtained in moderate to good yields.

引用

页码：3461 / 3469

页数：8

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