Chitotriosidase as a marker of disease activity in sarcoidosis

被引：0

作者：

Jürgen Brunner

Sabine Scholl-Bürgi

Martina Prelog

Lothar-Bernd Zimmerhackl

机构：

[1] Innsbruck Medical School,Division of Neonatology and Neuropediatrics, Department of Pediatrics

[2] Innsbruck Medical School,Division of Rheumatology, Nephrology, Infectiology and Endocrinology, Department of Pediatrics

来源：

Rheumatology International | 2007年 / 27卷

关键词：

Juvenile sarcoidosis; Chitotriosidase;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Sarcoidosis is a chronic granulomatous inflammation. The clinical spectrum in childhood is heterogeneous. Angiotensin converting enzyme activity is used as a marker for disease activity. Human chitotriosidase is produced in macrophages. In this study, serum chitotriosidase levels were significantly higher in active sarcoidosis than in inactive disease or healthy controls. Serum chitotriosidase concentrations may be a useful marker for monitoring disease activity in sarcoidosis.

引用

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