Therapeutic effect of osimertinib plus cranial radiotherapy compared to osimertinib alone in NSCLC patients with EGFR-activating mutations and brain metastases: a retrospective study

被引:0
|
作者
Xiaoyang Zhai
Wanhu Li
Ji Li
Wenxiao Jia
Wang Jing
Yaru Tian
Shuhui Xu
Yuying Li
Hui Zhu
Jinming Yu
机构
[1] Shantou University Medical College,Department of Radiation Oncology, Shandong Cancer Hospital and Institute
[2] Shandong First Medical University and Shandong Academy of Medical Sciences,Department of Radiology, Shandong Cancer Hospital and Institute
[3] Shandong First Medical University and Shandong Academy of Medical Sciences,Department of Oncology
[4] Renmin Hospital of Wuhan University,Department of Radiation Oncology
[5] Shandong Cancer Hospital and Institute Affiliated to Shandong University,undefined
[6] Shandong First Medical University,undefined
[7] Shandong Academy of Medical Sciences,undefined
来源
Radiation Oncology | / 16卷
关键词
Osimertinib; Cranial radiotherapy; Brain metastases; Leukoencephalopathy; Non-small cell lung cancer;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] The effect of savolitinib plus osimertinib on ctDNA clearance in patients with EGFR mutation positive (EGFRm) MET-amplified NSCLC in the TATTON study
    Hartmaier, Ryan
    Han, Ji-Youn
    Ahn, Myung-Ju
    Cho, Byoung Chul
    Cantarini, Mireille
    Frewer, Paul
    Frigault, Melanie M.
    Oxnard, Geoffrey
    CANCER RESEARCH, 2020, 80 (16)
  • [42] Local control of brain metastases with osimertinib alone in patients with EGFR-mutant non-small cell lung cancer
    Caressa Hui
    Vera Qu
    Jen-Yeu Wang
    Rie von Eyben
    Yu-Cheng Chang
    Po-Lin Chiang
    Chih-Hung Liang
    Jen-Tang Lu
    Gordon Li
    Melanie Hayden-Gephart
    Heather Wakelee
    Joel Neal
    Kavitha Ramchandran
    Millie Das
    Seema Nagpal
    Scott Soltys
    Nathaniel Myall
    Erqi Pollom
    Journal of Neuro-Oncology, 2022, 160 : 233 - 240
  • [43] Local Control of Brain Metastases with Osimertinib Alone in Patients with EGFR-Mutant Non-Small Cell Lung Cancer
    Hui, C.
    Qu, V.
    Wang, J. Y.
    Von Eyben, R.
    Chang, Y. C.
    Chiang, P. L.
    Liang, C. H.
    Lin, J. Y.
    Lu, J. T.
    Li, G.
    Hayden, M.
    Myall, N.
    Soltys, S. G.
    Pollom, E.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2022, 114 (03): : E54 - E55
  • [44] Local control of brain metastases with osimertinib alone in patients with EGFR-mutant non-small cell lung cancer
    Hui, Caressa
    Qu, Vera
    Wang, Jen-Yeu
    von Eyben, Rie
    Chang, Yu-Cheng
    Chiang, Po-Lin
    Liang, Chih-Hung
    Lu, Jen-Tang
    Li, Gordon
    Hayden-Gephart, Melanie
    Wakelee, Heather
    Neal, Joel
    Ramchandran, Kavitha
    Das, Millie
    Nagpal, Seema
    Soltys, Scott
    Myall, Nathaniel
    Pollom, Erqi
    JOURNAL OF NEURO-ONCOLOGY, 2022, 160 (01) : 233 - 240
  • [45] Osimertinib for EGFR-Mutant Lung Cancer with Brain Metastases: Results from a Single-Center Retrospective Study
    Xie, Lijia
    Nagpal, Seema
    Wakelee, Heather A.
    Li, Gordon
    Soltys, Scott G.
    Neal, Joel W.
    ONCOLOGIST, 2019, 24 (06): : 836 - 843
  • [46] Safety and efficacy of osimertinib plus bevacizumab as first-line treatment in EGFR-mutant NSCLC with brain metastases: A dynamic ctDNA-guided study
    Wei, Fang
    An, Juan
    Hua, Yichun
    Ding, Xiaosheng
    Sun, Shibin
    Li, Xiaoyan
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [47] Safety and Efficacy of Cranial Radiotherapy in Combination with Aumolertinibin EGFR-Mutant NSCLC Patients with Brain Metastases
    Han, S.
    Wang, W.
    Bi, N.
    JOURNAL OF THORACIC ONCOLOGY, 2024, 19 (10) : S590 - S590
  • [48] Uncommon EGFR mutations conducted with osimertinib in patients with NSCLC: a study protocol of phase 2 study (UNICORN/TCOG1901)
    Okuma, Yusuke
    Shimokawa, Mototsugu
    Hashimoto, Kana
    Mizutani, Hideaki
    Wakui, Hiroshi
    Murakami, Shuji
    Atagi, Shinji
    Minato, Koichi
    Seike, Masahiro
    Ohe, Yuichiro
    Kubota, Kaoru
    FUTURE ONCOLOGY, 2022, 18 (05) : 523 - 531
  • [49] EGFR-TKI Alone or with Concomitant Radiotherapy for Brain Metastases in Lung Adenocarcinoma Patients with EGFR Gene Mutations
    Chen, Yongshun
    Yang, Jing
    Li, Xue
    Hao, Daxuan
    Wu, Xiaoyuan
    Yang, Yuanyuan
    Hu, Xiaona
    He, Chunyu
    Wang, Wen
    Liu, Jinsong
    Wang, Jianhua
    JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (09) : S278 - S278
  • [50] Osimertinib for patients with EGFR-mutant advanced NSCLC and asymptomatic brain metastases: An open-label, two-arm, phase II study
    Gillis, R.
    Peled, N.
    Goldshtien, I.
    Rotem, O.
    Rozenblum, A. B.
    Nechushtan, H.
    Chen, L.
    Dudnik, E.
    Zer, A.
    Yust-Katz, S.
    Shelef, I.
    Roisman, L. C.
    Inbar, E.
    ANNALS OF ONCOLOGY, 2019, 30