Immunohistochemical analysis of EGF-R in gastric mucosa in portal hypertensive with cirrhosis

被引：0
|
作者：
C. Mba Mba
Yang Zhen
机构：
[1] Tongji Medical University,Department of General Surgery
来源：
Current Medical Science | 1997年 / 17卷 / 4期
关键词：
cirrhosis; portal hypertension; gastric mucosa; EGF-R; PAP, immunohistochemistry;
D O I：
10.1007/BF02895627
中图分类号：
学科分类号：
摘要：
PAP Immunohistochemical technique was used to detect the expression and distribution of EGF-R in gastric mucosa in portal hypertensive pigs with cirrhosis. Our result showed that the EGF-R content in gastric mucosa of portal hypertensive pigs was significantly lower than that in control group. Microscopically, the portal hypertension (PHT) group imparted “feeble positivity ” or “negative results ” and the control group showed “strong positivity ”. It was suggested that the decrease of EGF-R content in gastric mucosa weakened defense mechanism of gastric mucosa and increase its vulnerability. It is believed that the decreased EGF-R in gastric mucosa is ascribed to the lesions of gastric mucosa during PHT with cirrhosis.
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页码：232 / 234
页数：2
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