Immunohistochemical analysis of EGF-R in gastric mucosa in portal hypertensive with cirrhosis

被引：0
|
作者：
C. Mba Mba
Yang Zhen
机构：
[1] Tongji Medical University,Department of General Surgery
来源：
Current Medical Science | 1997年 / 17卷 / 4期
关键词：
cirrhosis; portal hypertension; gastric mucosa; EGF-R; PAP, immunohistochemistry;
D O I：
10.1007/BF02895627
中图分类号：
学科分类号：
摘要：
PAP Immunohistochemical technique was used to detect the expression and distribution of EGF-R in gastric mucosa in portal hypertensive pigs with cirrhosis. Our result showed that the EGF-R content in gastric mucosa of portal hypertensive pigs was significantly lower than that in control group. Microscopically, the portal hypertension (PHT) group imparted “feeble positivity ” or “negative results ” and the control group showed “strong positivity ”. It was suggested that the decrease of EGF-R content in gastric mucosa weakened defense mechanism of gastric mucosa and increase its vulnerability. It is believed that the decreased EGF-R in gastric mucosa is ascribed to the lesions of gastric mucosa during PHT with cirrhosis.
引用
收藏
页码：232 / 234
页数：2
相关论文
共 50 条
  • [1] Immunohistochemical Analysis of EGF-R in Gastric Mucosa in Portal Hypertensive with Cirrhosis
    杨镇
    Journal of Tongji Medical University, 1997, (04) : 232 - 234
  • [2] Immunohistochemical distribution of EGF and EGF-R in the dental follicle.
    Wilson, TG
    Norris, K
    Shroff, B
    JOURNAL OF DENTAL RESEARCH, 1997, 76 : 2809 - 2809
  • [3] PORTAL HYPERTENSIVE GASTRIC-MUCOSA
    BHASIN, DK
    KOCHHAR, R
    MEHTA, SK
    GUT, 1987, 28 (10) : 1324 - 1324
  • [4] Increased expression of EGF-receptor (EGF-R) and c-erbB-2 in the gastric mucosa of aged rats.
    Majumdar, APN
    Tureaud, J
    Reddy, KB
    Sarkar, F
    FASEB JOURNAL, 1997, 11 (03): : 3639 - 3639
  • [5] CYTOPROTECTION OF THE PORTAL HYPERTENSIVE GASTRIC-MUCOSA
    SANKARY, H
    TARNAWSKI, A
    SARFEH, IJ
    SURGICAL FORUM, 1984, 35 : 173 - 174
  • [6] Effect of teprenone on portal hypertensive gastric mucosa
    Tanoue, K
    Tarnawski, AS
    Kishihara, F
    Ohta, M
    Hashizume, M
    Sugimachi, K
    Sarfeh, IJ
    DIGESTION, 1996, 57 (01) : 35 - 40
  • [7] A Reappraisal of the Gastric Mucosa! Pathology in Portal Hypertensive Patients
    Ma, Changqing
    Chen, Chien-Huan
    Liu, Ta-Chiang
    MODERN PATHOLOGY, 2015, 28 : 176A - 176A
  • [8] Expression of adrenomedullin in portal hypertensive gastric mucosa of rats
    Tomikawa, M
    Wang, H
    Jones, MK
    Sugimachi, K
    Sarfeh, IJ
    Tarnawski, AS
    JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1998, 49 (02): : 319 - 328
  • [9] PORTAL HYPERTENSIVE GASTRIC-MUCOSA - AN ENDOSCOPIC STUDY
    PAPAZIAN, A
    BRAILLON, A
    DUPAS, JL
    SEVENET, F
    CAPRON, JP
    GUT, 1986, 27 (10) : 1199 - 1203
  • [10] A Reappraisal of the Gastric Mucosa! Pathology in Portal Hypertensive Patients
    Ma, Changqing
    Chen, Chien-Huan
    Liu, Ta-Chiang
    LABORATORY INVESTIGATION, 2015, 95 : 176A - 176A
12345