Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma

被引：0
|
作者：
Lina Y Dimberg
Anna Dimberg
Karolina Ivarsson
Mårten Fryknäs
Linda Rickardson
Gerard Tobin
Simon Ekman
Rolf Larsson
Urban Gullberg
Kenneth Nilsson
Fredrik Öberg
Helena Jernberg Wiklund
机构：
[1] Rudbeck Laboratory,Department of Immunology, Genetics and Pathology
[2] Uppsala University,Department of Medical Sciences
[3] Uppsala University,Department of Laboratory Medicine
[4] Lund University,undefined
来源：
BMC Cancer | / 12卷
关键词：
Hematopoetic malignancies; Multiple myeloma; Apoptosis; IFN; Stat1; Stat3; Drug sensitivity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] PML suppresses IL-6-induced STAT3 activation by interfering with STAT3 and HDAC3 interaction
    Kato, Masaya
    Muromoto, Ryuta
    Togi, Sumihito
    Iwakami, Masashi
    Kitai, Yuichi
    Kon, Shigeyuki
    Oritani, Kenji
    Matsuda, Tadashi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 461 (02) : 366 - 371
  • [42] Gain of STAT1 Signaling Associated with Overlapping Pathophysiology in STAT3, IL21R and STAT1 Mutant Patients
    Lopez, Diego B.
    Milner, Joshua D.
    JOURNAL OF CLINICAL IMMUNOLOGY, 2014, 34 (03) : 370 - 370
  • [43] Proinflammatory Cytokines IL-6 and TNF-α Increased Telomerase Activity through NF-κB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells
    Chung, Seyung S.
    Wu, Yong
    Okobi, Quincy
    Adekoya, Debbie
    Atefi, Mohammad
    Clarke, Orette
    Dutta, Pranabananda
    Vadgama, Jaydutt V.
    MEDIATORS OF INFLAMMATION, 2017, 2017
  • [44] NF-κB INDUCED IL-6 ENSURES STAT3 ACTIVATION AND TUMOR AGGRESSIVENESS IN GLIOBLASTOMA
    McFarland, Braden C.
    Hong, Suk W.
    Rajbhandari, Rajani
    Twitty, George B.
    Gray, G. Kenneth
    Yu, Hao
    Benveniste, Etty N.
    Nozell, Susan E.
    NEURO-ONCOLOGY, 2013, 15 : 23 - 23
  • [45] NF-κB INDUCED IL-6 ENSURES STAT3 ACTIVATION AND TUMOR AGGRESSIVENESS IN GLIOBLASTOMA
    McFarland, Braden C.
    Hong, Suk W.
    Rajbhandari, Rajani
    Twitty, George B., Jr.
    Gray, G. Kenneth
    Yu, Hao
    Langford, Catherine P.
    Gillespie, G. Yancey
    Benveniste, Etty N.
    Nozell, Susan E.
    NEURO-ONCOLOGY, 2012, 14 : 7 - 7
  • [46] STAT3 signaling induced by the IL-6 family of cytokines modulates angiogenesis
    Rapp, Julian
    Jung, Malte
    Klar, Rhena F. U.
    Wolf, Julian
    Arnold, Jakob
    Gorka, Oliver
    Gross, Olaf
    Lange, Clemen
    Agostini, Hansjurgen
    Schlunck, Guenther
    Bucher, Felicitas
    JOURNAL OF CELL SCIENCE, 2023, 136 (01)
  • [47] Peptide YY attenuates STAT1 and STAT3 activation induced by TNF-α in acinar cell line AR42J
    Robinson, K
    Vona-Davis, L
    Riggs, D
    Jackson, B
    McFadden, D
    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2006, 202 (05) : 788 - 796
  • [48] IL-6 PROMOTES MYC-INDUCED LYMPHOMAGENESIS INDEPENDENT OF STAT3
    Marshall, N. Reich
    Mena-Taboada, P.
    Poli, V.
    Petrenko, A.
    CYTOKINE, 2016, 87 : 112 - 113
  • [49] Upregulated production of IL-6, but not IL-10, by interferon-α induces SOCS3 expression and attenuates STAT1 phosphorylation in myeloma cells
    Usui, E
    Nishii, K
    Katayama, N
    Lorenzo, F
    Chen, FW
    Monma, F
    Otsuki, T
    Shiku, H
    HEMATOLOGY JOURNAL, 2004, 5 (06) : 505 - 512
  • [50] PHENOLIC COMPOUNDS ISOLATED FROM PSOLALEA CORYIFOLIA INHIBIT IL-6 INDUCED STAT3 ACTIVATION
    Lee, Seung Woong
    Yun, Bo Ra
    Oh, Hyun-Mee
    Rho, Mun-Chual
    PHARMACEUTICAL BIOLOGY, 2012, 50 (05) : 555 - 555
12345