GADD45α alleviates acetaminophen-induced hepatotoxicity by promoting AMPK activation

被引：0
|
作者：
Chunmin Li
Yanan Ming
Zhengyang Wang
Qingling Xu
Lvfeng Yao
Dongke Xu
Yingyue Tang
Xiaohong Lei
Xiaobo Li
Yimin Mao
机构：
[1] Shanghai Jiao Tong University,Division of Gastroenterology and Hepatology, School of Medicine, Shanghai Institute of Digestive Disease, Renji Hospital
[2] Fudan University,Department of Physiology and Pathophysiology, School of Basic Medical Sciences
[3] Zhengzhou University,Department of Pathology, The First Affiliated Hospital of Zhengzhou University
[4] Fujian Medical University,Department of Hepatology, Mengchao Hepatobiliary Hospital
来源：
Cellular and Molecular Life Sciences | 2019年 / 76卷
关键词：
Acetaminophen (APAP); Drug-induced liver injury (DILI); GADD45α; AMPK;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：129 / 145
页数：16
相关论文
共 50 条
  • [41] CHOP is a critical regulator of acetaminophen-induced hepatotoxicity
    Uzi, Dotan
    Barda, Liran
    Scaiewicz, Viviana
    Mills, Maya
    Mueller, Tobias
    Gonzalez-Rodriguez, Agueda
    Valverde, Angela M.
    Iwawaki, Takao
    Nahmias, Yaacov
    Xavier, Ramnik
    Chung, Ray T.
    Tirosh, Boaz
    Shibolet, Oren
    JOURNAL OF HEPATOLOGY, 2013, 59 (03) : 495 - 503
  • [42] Role of innate immunity in acetaminophen-induced hepatotoxicity
    Liu, Zhang-Xu
    Kaplowitz, Neil
    EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2006, 2 (04) : 493 - 503
  • [43] New potential biomarkers of acetaminophen-induced hepatotoxicity
    Siemionow, Katarzyna
    Teul, Joanna
    Dragowski, Pawel
    Palka, Jerzy
    Miltyk, Wojciech
    ADVANCES IN MEDICAL SCIENCES, 2016, 61 (02): : 325 - 330
  • [44] Effects of Photoperiod on Acetaminophen-Induced Hepatotoxicity in Mice
    Lu, Jihong
    Wang, Hu
    Zhang, Rumeng
    Wan, Zhikang
    Gao, Hang
    Cai, Jie
    Cheng, Yujia
    Pu, Dong
    Lin, Tengfei
    Fan, Chenyu
    Sun, Ying
    DIGESTIVE DISEASES AND SCIENCES, 2020, 65 (01) : 178 - 188
  • [45] Effects of erdosteine on acetaminophen-induced hepatotoxicity in rats
    Sogut, S.
    Duru, M.
    Kuvandik, G.
    Kaya, H.
    CLINICAL CHEMISTRY, 2007, 53 (06) : A159 - A159
  • [46] Sulforaphane protects against acetaminophen-induced hepatotoxicity
    Noh, Jung-Ran
    Kim, Yong-Hoon
    Hwang, Jung Hwan
    Choi, Dong-Hee
    Kim, Kyoung-Shim
    Oh, Won-Keun
    Lee, Chul-Ho
    FOOD AND CHEMICAL TOXICOLOGY, 2015, 80 : 193 - 200
  • [47] Necrosis Versus Apoptosis in Acetaminophen-Induced Hepatotoxicity
    Schulze-Osthoff, Klaus
    Bantel, Heike
    HEPATOLOGY, 2011, 53 (03) : 1070 - 1070
  • [48] Proteomic analysis of acetaminophen-induced hepatotoxicity in rats
    Gao, Yuan
    Yang, Xi
    Salminen, William
    Mendrick, Donna L.
    Yu, Li-Rong
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [49] Comment on "Thromboelastography in the setting of acetaminophen-induced hepatotoxicity"
    Siddiqui, Suhail Sarwar
    Chakraborty, Nilanchal
    Muzaffar, Syed Nabeel
    Gurjar, Mohan
    CLINICAL TOXICOLOGY, 2022, 60 (07) : 889 - 890
  • [50] Selective protein arylation and acetaminophen-induced hepatotoxicity
    Cohen, SD
    Khairallah, EA
    DRUG METABOLISM REVIEWS, 1997, 29 (1-2) : 59 - 77
12345