(Pro)renin receptor mediates tubular epithelial cell pyroptosis in diabetic kidney disease via DPP4-JNK pathway

被引：0
|
作者：
Shiying Xie
Shicong Song
Sirui Liu
Qiong Li
Wei Zou
Jianting Ke
Cheng Wang
机构：
[1] The Fifth Affiliated Hospital Sun Yat-Sen University,Division of Nephrology, Department of Medicine
[2] The Fifth Affiliated Hospital Sun Yat-Sen University,Guangdong Provincial Engineering Research Center of Molecular Imaging Center
来源：
Journal of Translational Medicine | / 22卷
关键词：
(Pro)renin receptor; Diabetic kidney disease; Renal tubular cell pyroptosis; Dipeptidyl peptidase 4;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Reticulon-1A mediates diabetic kidney disease progression through endoplasmic reticulum-mitochondrial contacts in tubular epithelial cells
    Xie, Yifan
    Jing, E.
    Cai, Hong
    Zhong, Fang
    Xiao, Wenzhen
    Gordon, Ronald E.
    Wang, Lois
    Zheng, Ya-Li
    Zhang, Aihua
    Lee, Kyung
    He, John Cijiang
    KIDNEY INTERNATIONAL, 2022, 102 (02) : 293 - 306
  • [22] TUBULAR EPITHELIAL CELL APOPTOSIS IN THE OBSTRUCTED MOUSE KIDNEY IS DEPENDENT UPON SIGNALLING VIA JNK1 AND MKK3
    Ma, F.
    Tesch, G. H.
    Flavell, R. A.
    Davis, R. J.
    Nikolic-Paterson, D. J.
    NEPHROLOGY, 2006, 11 : A3 - A3
  • [23] Trigonelline inhibits tubular epithelial-mesenchymal transformation in diabetic kidney disease via targeting Smad7
    Gong, Minmin
    Guo, Yujin
    Dong, Hui
    Wu, Wenbin
    Wu, Fan
    Lu, Fuer
    BIOMEDICINE & PHARMACOTHERAPY, 2023, 168
  • [24] TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease
    Wang, Youliang
    Zhu, Xuejing
    Yuan, Shuguang
    Wen, Si
    Liu, Xuemei
    Wang, Chang
    Qu, Zhong
    Li, Jun
    Liu, Hong
    Sun, Lin
    Liu, Fuyou
    FRONTIERS IN ENDOCRINOLOGY, 2019, 10
  • [25] Soluble (Pro)renin Receptor Induces Endothelial Cell Injury via Activation of Nox4/NF-[kappa]B Pathway.
    Fu, Ziwei
    Hu, Jiajia
    Wang, Fei
    Su, Jiahui
    Lu, Xiaohan
    Yang, Tianxin
    HYPERTENSION, 2017, 70
  • [26] (Pro)renin Receptor (PRR) Mediates High Fat Diet-induced Hypertension via Upregulation of Epithelial Sodium Channel & Aquaporin-2
    Quadri, Syed S.
    Culver, Silas A.
    Siragy, Helmy M.
    HYPERTENSION, 2016, 68
  • [27] Tissue Kallikrein Mediates Pro-Inflammatory Pathways and Activation of Protease-Activated Receptor-4 in Proximal Tubular Epithelial Cells
    Yiu, Wai Han
    Wong, Dickson W. L.
    Chan, Loretta Y. Y.
    Leung, Joseph C. K.
    Chan, Kwok Wah
    Lan, Hui Yao
    Lai, Kar Neng
    Tang, Sydney C. W.
    PLOS ONE, 2014, 9 (02):
  • [28] RTNA1 Mediates the Diabetic Kidney Disease Progression Through Endoplasmic Reticulum (ER) Mitochondrial Contacts in Renal Tubular Epithelial Cells
    Zhong, Fang
    Lee, Kyung
    He, John C.
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021, 32 (10): : 26 - 26
  • [29] S-nitrosoglutathione inhibits pyroptosis of kidney tubular epithelial cells in sepsis via the SIRT3/SOD2/mtROS signaling pathway
    Fan, Heng
    Sun, Min
    Zhu, Jian-hua
    RENAL FAILURE, 2025, 47 (01)
  • [30] USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway
    Zhu, Suwei
    Hou, Shaoshuai
    Lu, Yao
    Sheng, Wei
    Cui, Zhengguo
    Dong, Tianyi
    Feng, Hong
    Wan, Qiang
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 9
12345