Detection of P2X purinergic receptors on human B lymphocytes

被引：0

作者：

Ronald Sluyter

Julian A. Barden

James S. Wiley

机构：

[1] Department of Medicine,

[2] University of Sydney,undefined

[3] Clinical Sciences Building,undefined

[4] Nepean Hospital,undefined

[5] Penrith,undefined

[6] NSW 2750,undefined

[7] Australia,undefined

[8] Institute for Biomedical Research,undefined

[9] Department of Anatomy and Histology,undefined

[10] F13,undefined

[11] University of Sydney,undefined

[12] NSW 2006,undefined

[13] Australia,undefined

来源：

Cell and Tissue Research | 2001年 / 304卷

关键词：

P2X purinoceptor ATP-gated ion channel B lymphocyte Polyclonal antibody Confocal microscopy Human;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

B lymphocytes are known to synthesise the P2X7 subtype of the P2X purinergic receptor family; however, the identification of the other six P2X subtypes on these cells has been limited by the absence of specific antibodies. In this study, we used a panel of anti-P2X polyclonal antibodies and confocal microscopy to examine the presence of each P2X receptor on human B lymphocytes. We observed that P2X1, P2X2, P2X4 and P2X7 subtypes, but not P2X3, P2X5 and P2X6 subtypes, are present on B lymphocytes.

引用

页码：231 / 236

页数：5

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