LTR retrotransposons as source of promoters in the drosophila genome

被引：0
|
作者：
I. V. Makunin
A. A. Yurlova
机构：
[1] Russian Academy of Science,Institute of Chemical Biology and Fundamental Medicine, Siberian Branch
来源：
Russian Journal of Genetics | 2010年 / 46卷
关键词：
Transposable Element; Terminal Repeat; UCSC Genome Browser; Mouse Oocyte; Drosophila Genome;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Mobile genetic elements affect genome structure and function in various ways. Significant number of genes in human and mouse are transcribed from alternative promoters located in LTR retrotransposons. As a rule, these retrotransposons are located upstream of annotated genes, and their promoters initiate transcription of alternative first exons. We investigated role of LTR retrotransposons in expression of genes in Drosophila. Using database of spliced ESTs we identified only 13 potential cases of transcription initiation from long terminal repeats of LTR retrotransposons within euchromatic part of the Drosophila genome. Our results indicate on insignificant role of promoters of LTR retrotransposons in expression of genes in Drosophila.
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页码：1067 / 1069
页数：2
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