Cerebellar granule cells acquire a widespread predictive feedback signal during motor learning

被引：0

作者：

Andrea Giovannucci

Aleksandra Badura

Ben Deverett

Farzaneh Najafi

Talmo D Pereira

Zhenyu Gao

Ilker Ozden

Alexander D Kloth

Eftychios Pnevmatikakis

Liam Paninski

Chris I De Zeeuw

Javier F Medina

Samuel S-H Wang

机构：

[1] Princeton University,Princeton Neuroscience Institute and Department of Molecular Biology

[2] Center for Computational Biology,Department of Biology

[3] Flatiron Institute,Department of Neuroscience

[4] Simons Foundation,Departments of Statistics and Neuroscience

[5] Netherlands Institute for Neuroscience,Department of Neuroscience

[6] Robert Wood Johnson Medical School,undefined

[7] University of Pennsylvania,undefined

[8] Erasmus MC,undefined

[9] School of Engineering,undefined

[10] Brown University,undefined

[11] Columbia University,undefined

[12] Baylor College of Medicine,undefined

[13] Present addresses: Cold Spring Harbor Laboratory,undefined

[14] Cold Spring Harbor,undefined

[15] New York,undefined

[16] USA (F.N.) and University of North Carolina,undefined

[17] Chapel Hill,undefined

[18] North Carolina,undefined

[19] USA (A.D.K.).,undefined

来源：

Nature Neuroscience | 2017年 / 20卷

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学科分类号：

摘要：

Granule cells constitute half of the cells in the brain, yet their activity during behavior is largely uncharacterized. The authors report that granule cells encode multisensory representations that evolve with learning into a predictive motor signal. This activity may help the cerebellum implement a forward model for action.

引用

页码：727 / 734

页数：7

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