Biopotentials of secondary metabolites isolated from marine sponges

被引：0
|
作者：
Joseph Selvin
A.P. Lipton
机构：
[1] Malankara Catholic College,Department of Biotechnology
[2] Central Marine Fisheries Research Institute,Marine Biotechnology Laboratory
来源：
Hydrobiologia | 2004年 / 513卷
关键词：
sponge; secondary-metabolites; antibacterial; brineshrimp-cytotoxicity; larvicidal; antifouling; ichthyotoxic;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The secondary metabolites of three sponges collected as bycatch in the fishing nets were explored for biological potencies. The sponge Dendrilla nigraexhibited wider biological activity. It showed potent activity in antibacterial, brineshrimp cytotoxicity, larvicidal, antifouling and ichthyotoxic assays. One of the well-studied cytotoxic sponge Axinella donnaniwas least active in brineshrimp cytotoxicity assay. The secondary metabolites of Clathria gorgonoideswere highly cytotoxic albeit it showed least activity in other bioassays. Based on the present findings, it could be inferred that the bioassay-guided fractionation and purification of D. nigramay come up with potent bioactive drugs. %
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页码：231 / 238
页数：7
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