Role of Nitric Oxide and Lipid Peroxidation in Mechanisms of Febrile Convulsions in Wistar Rat Pups

被引：0
|
作者：
Yu. A. Klyueva
V. G. Bashkatova
G. Yu. Vitskova
V. B. Narkevich
V. D. Mikoyan
A. F. Vanin
S. A. Chepurnov
N. E. Chepurnova
机构：
[1] M. V. Lomonosov Moscow State University,Department of Human and Animal Physiology, Biological Faculty
[2] Russian Academy of Medical Sciences,Laboratory of Neurochemical Pharmacology, Institute of Pharmacology
[3] Russian Academy of Sciences,Laboratory of Physical Chemistry of Polymers, Institute of Chemical Physics
来源：
Bulletin of Experimental Biology and Medicine | 2001年 / 131卷
关键词：
febrile convulsions; nitric oxide; N-nitro-L-arginine; lipid peroxidation; EPR spectroscopy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Generation of nitric oxide and the content of lipid peroxidation products in the brain are increased in rat pups during febrile convulsions. NO-synthase inhibitor N-nitro-L-arginine in a dose of 250 mg/kg prevented hyperthermia-induced accumulation of nitric oxide, increased the latency febrile convulsions, and had no effect on the content of lipid peroxidation products.
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页码：47 / 49
页数：2
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