From worm genetic networks to complex human diseases

被引：0
|
作者：
Howard Bussey
Brenda Andrews
Charles Boone
机构：
[1] McGill University,Biology Department
[2] University of Toronto,Banting and Best Department of Medical Research and Department of Medical Genetics and Microbiology
来源：
Nature Genetics | 2006年 / 38卷
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学科分类号：
摘要：
Systematic mapping of genetic interactions for Caenorhabditis elegans genes involved in signaling pathways implicated in human disease reveals a network of 350 interactions. The topology of this network resembles that mapped previously in yeast, reinforcing the idea that similar networks may underlie the genetic basis of complex human disease.
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页码：862 / 863
页数：1
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