Discovery: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria

被引:0
|
作者
Fourie Joubert
Claudia M Harrison
Riaan J Koegelenberg
Christiaan J Odendaal
Tjaart AP de Beer
机构
[1] University of Pretoria,Bioinformatics and Computational Biology Unit, Department of Biochemistry
来源
关键词
Malaria; Dihydrofolate Reductase; Plasmodium Species; Discovery System; Pyrimethamine;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery
    Zhu, Feng
    Shi, Zhe
    Qin, Chu
    Tao, Lin
    Liu, Xin
    Xu, Feng
    Zhang, Li
    Song, Yang
    Liu, Xianghui
    Zhang, Jingxian
    Han, Bucong
    Zhang, Peng
    Chen, Yuzong
    [J]. NUCLEIC ACIDS RESEARCH, 2012, 40 (D1) : D1128 - D1136
  • [22] Target selection in drug discovery - Making tough decisions in a tough climate
    Fitzgerald, D
    Gromo, G
    [J]. SCIENTIST, 2004, 18 (15): : 36 - 37
  • [23] Anopheles gambiae Genome Conservation as a Resource for Rational Gene Drive Target Site Selection
    Kranjc, Nace
    Crisanti, Andrea
    Nolan, Tony
    Bernardini, Federica
    [J]. INSECTS, 2021, 12 (02) : 1 - 12
  • [24] Trafficking of Plasmodium Falciparum Proteins: A Novel Anti-Malaria Drug Target?
    Coetzer, Theresa L.
    Churchyard, Alisje
    Wepener, Melanie
    [J]. BLOOD, 2016, 128 (22)
  • [25] Chemogenomics in malaria: Using systems approaches in chemical biology and drug target discovery.
    Kuhen, Kelli
    Plouffe, David
    Henson, Kerstin
    Chen, Zhong
    Chatterjee, Amab
    Nagle, Advait
    Matzen, Jason
    Anderson, Paul
    Brinker, Achim
    Winzeler, Elizabeth
    [J]. INTERNATIONAL JOURNAL FOR PARASITOLOGY, 2008, 38 : S96 - S96
  • [26] TARGET-BASED DRUG DISCOVERY IN MALARIA: A NEW WAY TO IMPLEMENT AN OLD STRATEGY
    Alvaro, Elena Fernandez
    Harupa, Anke
    Kaushansky, Alexis
    Penzo, Maria
    Penzo, Maria
    Baker, David
    Herreros, Esperanza
    Ballell-Pages, Lluis
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2017, 95 (05): : 90 - 90
  • [27] Prioritizing and modelling of putative drug target proteins of Candida albicans by systems biology approach
    Ismail, Tariq
    Fatima, Nighat
    Muhammad, Syed Aun
    Zaidi, Syed Saoud
    Rehman, Nisar
    Hussain, Izhar
    Tariq, Najam Us Sahr
    Amirzada, Imran
    Mannan, Abdul
    [J]. ACTA BIOCHIMICA POLONICA, 2018, 65 (02) : 209 - 218
  • [28] rational drug design plays big part in drug discovery - Companies target bottlenecks in the optimization of lead compounds
    Glaser, V
    [J]. GENETIC ENGINEERING NEWS, 1998, 18 (19): : 1 - +
  • [29] Microfluidics for drug discovery and development: From target selection to product lifecycle management
    Kang, Lifeng
    Chung, Bong Geun
    Langer, Robert
    Khademhosseini, Ali
    [J]. DRUG DISCOVERY TODAY, 2008, 13 (1-2) : 1 - 13
  • [30] Computer-aided target selection - prioritizing targets for antifungal drug discovery
    Spaltmann, F
    Blunck, M
    Ziegelbauer, K
    [J]. DRUG DISCOVERY TODAY, 1999, 4 (01) : 17 - 26