Inhibition of CCR2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the PI3K/Akt pathway

被引：0
|
作者：
Qi Tian
Yujia Guo
Shi Feng
Chengli Liu
Peibang He
Jianfeng Wang
Wenrui Han
Chen Yang
Zhan Zhang
Mingchang Li
机构：
[1] Renmin Hospital of Wuhan University,Department of Neurosurgery
[2] Renmin Hospital of Wuhan University,Department of Rehabilitation
来源：
Journal of Neuroinflammation | / 19卷
关键词：
Apoptosis; CCR2; Inflammation; Neuron; Subarachnoid hemorrhage;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [11] Aggf1 attenuates neuroinflammation and BBB disruption via PI3K/Akt/NF-κB pathway after subarachnoid hemorrhage in rats
    Qiquan Zhu
    Budbazar Enkhjargal
    Lei Huang
    Tongyu Zhang
    Chengmei Sun
    Zhiyi Xie
    Pei Wu
    Jun Mo
    Jiping Tang
    Zongyi Xie
    John H. Zhang
    Journal of Neuroinflammation, 15
  • [12] Aggf1 attenuates neuroinflammation and BBB disruption via PI3K/Akt/NF-κB pathway after subarachnoid hemorrhage in rats
    Zhu, Qiquan
    Enkhjargal, Budbazar
    Huang, Lei
    Zhang, Tongyu
    Sun, Chengmei
    Xie, Zhiyi
    Wu, Pei
    Mo, Jun
    Tang, Jiping
    Xie, Zongyi
    Zhang, John H.
    JOURNAL OF NEUROINFLAMMATION, 2018, 15
  • [13] ACE2 Rescues Impaired Autophagic Flux Through the PI3K/AKT Pathway After Subarachnoid Hemorrhage
    Lujun Pang
    Zhao Liu
    Ke Zhou
    Peng Chen
    Enyu Pan
    Yanjun Che
    Xin Qi
    Neurochemical Research, 2022, 47 : 601 - 612
  • [14] ACE2 Rescues Impaired Autophagic Flux Through the PI3K/AKT Pathway After Subarachnoid Hemorrhage
    Pang, Lujun
    Liu, Zhao
    Zhou, Ke
    Chen, Peng
    Pan, Enyu
    Che, Yanjun
    Qi, Xin
    NEUROCHEMICAL RESEARCH, 2022, 47 (03) : 601 - 612
  • [15] Electroacupuncture improves cognitive impairment after subarachnoid hemorrhage in rats through the PI3K/AKT signaling pathway
    Zhou, Feng
    Wang, Zhenzhi
    Xiong, Kang
    Fu, Xiaoman
    Jiang, Hongru
    Zhang, Meiling
    Wang, Qiang
    Wang, Yuan
    ACUPUNCTURE IN MEDICINE, 2025, 43 (01) : 26 - 37
  • [16] Recombinant OX40 attenuates neuronal apoptosis through OX40-OX40L/PI3K/AKT signaling pathway following subarachnoid hemorrhage in rats
    Wu, Ling-Yun
    Enkhjargal, Budbazar
    Xie, Zhi-Yi
    Trayis, Zachary D.
    Sun, Cheng-Mei
    Zhou, Ke-Ren
    Zhang, Tong-Yu
    Zhu, Qi-Quan
    Hang, Chun-Hua
    Zhang, John H.
    EXPERIMENTAL NEUROLOGY, 2020, 326
  • [17] Agonism of the α7-acetylcholine receptor/PI3K/Akt pathway promotes neuronal survival after subarachnoid hemorrhage in mice
    Dienel, Ari
    Veettil, Remya A.
    Matsumura, Kanako
    Choi, H. Alex
    Kumar, Peeyush T.
    Tsvetkov, Andrey S.
    Aronowski, Jaroslaw
    Dash, Pramod
    Blackburn, Spiros L.
    McBride, Devin W.
    EXPERIMENTAL NEUROLOGY, 2021, 344
  • [18] Inhibition of CCR1 attenuates neuroinflammation via the JAK2/STAT3 signaling pathway after subarachnoid hemorrhage
    Tian, Qi
    Li, Yina
    Feng, Shi
    Liu, Chengli
    Guo, Yujia
    Wang, Guijun
    Wei, Heng
    Chen, Zhibiao
    Gu, Lijuan
    Li, Mingchang
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 125
  • [19] Propofol Reduces Inflammatory Brain Injury after Subarachnoid Hemorrhage: Involvement of PI3K/Akt Pathway
    Zhang, Hua-bin
    Tu, Xian-kun
    Chen, Quan
    Shi, Song-sheng
    JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2019, 28 (12):
  • [20] Simvastatin attenuates cerebral vasospasm and improves outcomes by upregulation of PI3K/Akt pathway in a rat model of subarachnoid hemorrhage
    Sugawara, Takashi
    Jadhav, Vikram
    Ayer, Robert
    Zhang, John
    INTRACRANIAL PRESSURE AND BRAIN MONITORING XIII: MECHANISMS AND TREATMENT, 2008, 102 : 391 - 394
12345