Tonic and phasic activity in smooth muscle

We have studied the electrical and mechanical behaviour of two very different smooth muscle preparations, mesenteric lymphatic ducts and proximal urethra. These tissues generate different patterns of spontaneous contraction adapted to fulfil their contrasting functions. While lymphatics undergo regular phasic contractions and relaxations, suited to their role in propelling lymph, the urethra remains in a state of contracture to maintain urinary continence. The challenge is to understand how both of these achieve their respective roles.