microRNA-29b prevents renal fibrosis by attenuating renal tubular epithelial cell–mesenchymal transition through targeting the PI3K/AKT pathway

被引:2
|
作者
Shuang Hu
Hongtao Hu
Rui Wang
Hong He
Hua Shui
机构
[1] Zhongnan Hospital,Department of Nephrology
[2] Wuhan University,Department of Nephrology
[3] Tongji Medical College,Department of Intensive Care Unit
[4] Wuhan Central Hospital,undefined
[5] Huazhong University of Science and Technology,undefined
[6] Zhongnan Hospital,undefined
[7] Wuhan University,undefined
来源
关键词
Unilateral ureteral obstruction; Angiotensin-II; NRK-52E cells; MicroRNA-29b; Phosphatidylinositol 3-kinase/protein kinase B; Epithelial–mesenchymal transition;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1941 / 1950
页数:9
相关论文
共 50 条
  • [31] Swainsonine induces autophagy via PI3K/AKT/mTOR signaling pathway to injure the renal tubular epithelial cells
    Wang, Shuai
    Wang, Jinglong
    Yang, Lin
    Guo, Rong
    Huang, Enxia
    Yang, Hanqi
    Zhang, Yajing
    Sun, Lu
    Song, Runjie
    Chen, Jingshu
    Tian, Yanan
    Zhao, Baoyu
    Guo, Qingyun
    Lu, Hao
    BIOCHIMIE, 2019, 165 : 131 - 140
  • [32] Nrf2 signaling attenuates epithelial-to-mesenchymal transition and renal interstitial fibrosis via PI3K/Akt signaling pathways
    Wang, Jun
    Zhu, Haobo
    Huang, Liqu
    Zhu, Xiaojiang
    Sha, Jintong
    Li, Guogen
    Ma, Geng
    Zhang, Wei
    Gu, Min
    Guo, Yunfei
    EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2019, 111
  • [33] MicroRNA-29b suppresses TGF-β-induced epithelial-mesenchymal transition in renal interstitium of spontaneously hypertensive rats
    Wu, Yihao
    Zhang, Zhi
    Chen, Zhe
    Fu, Chen
    Huang, Lu
    Wang, Jiabing
    Li, Jian
    Barszczyk, Andrew
    Yang, Deye
    CHINESE MEDICAL JOURNAL, 2022, 135 (07) : 857 - 859
  • [34] MicroRNA-328 Inhibits Renal Tubular Cell Epithelial-to-Mesenchymal Transition by Targeting the CD44 in Pressure-Induced Renal Fibrosis
    Chen, Cheng-Hsien
    Cheng, Chung-Yi
    Chen, Yen-Cheng
    Sue, Yuh-Mou
    Liu, Chung-Te
    Cheng, Tzu-Hurng
    Hsu, Yung-Ho
    Chen, Tso-Hsiao
    PLOS ONE, 2014, 9 (06):
  • [35] MicroRNA-381 inhibits lung adenocarcinoma cell biological progression by directly targeting LMO3 through regulation of the PI3K/Akt signaling pathway and epithelial-to-mesenchymal transition
    Xuan, Y-W
    Liao, M.
    Zhai, W-L
    Peng, L-J
    Tang, Y.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2019, 23 (19) : 8411 - 8421
  • [36] MicroRNA-29b suppresses TGF-β-induced epithelial-mesenchymal transition in renal interstitium of spontaneously hypertensive rats
    Wu Yihao
    Zhang Zhi
    Chen Zhe
    Fu Chen
    Huang Lu
    Wang Jiabing
    Li Jian
    Barszczyk Andrew
    Yang Deye
    中华医学杂志英文版, 2022, 135 (07) : 857 - 859
  • [37] Triptolide Attenuates Renal Tubular Epithelial-mesenchymal Transition Via the MiR-188-5p-mediated PI3K/AKT Pathway in Diabetic Kidney Disease
    Xue, Mei
    Cheng, Ying
    Han, Fei
    Chang, Yunpeng
    Yang, Yang
    Li, Xiaoyu
    Chen, Li
    Lu, Yunhong
    Sun, Bei
    Chen, Liming
    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018, 14 (11): : 1545 - 1557
  • [39] MicroRNA-29b Prevents Liver Fibrosis by Attenuating Hepatic Stellate Cell Activation and Inducing Apoptosis In Vitro and in Mice
    Wang, Jia
    Chu, Eagle S. H.
    Lan, Hui-Yao
    Sung, Joseph J. Y.
    Yu, Jun
    GASTROENTEROLOGY, 2013, 144 (05) : S938 - S938
  • [40] Targeting the PI3K/Akt/mTOR signalling pathway in Cystic Fibrosis
    R. Reilly
    M. S. Mroz
    E. Dempsey
    K. Wynne
    S. J. Keely
    E. F. McKone
    C. Hiebel
    C. Behl
    J. A. Coppinger
    Scientific Reports, 7