Significance of magnetic resonance image and blood manganese measurement for the assessment of brain manganese during total parenteral nutrition in rats

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作者
Hirotaka Chaki
Akihiko Matsuda
Kenji Yamamoto
Yukifumi Kokuba
Mikiko Kataoka
Yasuhisa Fujibayashi
Tsuyoshi Matsuda
Kazutaka Yamamoto
机构
[1] Hoechst Marion Roussel Ltd.,Infusion Research Department, Medical Information and Development Division
[2] Kyoto University,Department of Genetic Biochemistry, Faculty of Pharmaceutical Sciences
[3] Fukui Medical School,Department of Radiology
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关键词
Manganese; blood manganese; brain manganese; magnetic resonance image; total parenteral nutrition; trace element preparation;
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摘要
In this study, we report on the influence of trace elements (TE) on signal intensities of nuclear magnetic resonance images (MRI), both in vivo and in vitro. Optimal parameters for the assessment of Mn concentration in the brain of rats on total parenteral nutrition were established.
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页码:37 / 50
页数:13
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