Synthesis and anti-influenza activity of synthetic ribonucleases

被引:0
|
作者
L. S. Koroleva
N. S. Svishcheva
E. A. Burakova
N. V. Gribkova
N. P. Schmeleva
L. M. Rustamova
V. M. Sabynin
V. N. Sil’nikov
机构
[1] Russian Academy of Medical Sciences,Institute of Chemical Biology and Fundamental Medicine, Siberian Branch
[2] Novosibirsk State University,undefined
[3] Research Institute for Epidemiology and Microbiology,undefined
来源
关键词
synthetic ribonucleases; antiviral activity;
D O I
暂无
中图分类号
学科分类号
摘要
The acute toxicity and antiviral activity of synthetic ribonucleases with various structures have been studied. It is established that synthetic ribonucleases exhibit low toxicity with respect to MDCK cell cultures and inhibit to different extents the reproduction of influenza A and B type viruses.
引用
收藏
页码:679 / 682
页数:3
相关论文
共 50 条
  • [31] Synthesis and anti-influenza virus activity of tricyclic compounds with a unique amine moiety
    Oka, M
    Ishiwata, Y
    Iwata, N
    Honda, N
    Kakigami, T
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2001, 49 (04) : 379 - 383
  • [32] Design, Synthesis and Biological Activity of Novel Chalcone Derivatives as Anti-influenza Agents
    Shi Fangyuan
    Fang Hao
    Xu Wenfang
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2016, 32 (01) : 28 - 34
  • [33] Synthesis of Tamiflu and its phosphonate congeners possessing potent anti-influenza activity
    Shie, Jiun-Jie
    Fang, Jim-Min
    Wang, Shi-Yun
    Tsai, Keng-Chang
    Cheng, Yih-Shyun E.
    Yang, An-Suei
    Hsiao, Shih-Chia
    Su, Ching-Yao
    Wong, Chi-Huey
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (39) : 11892 - +
  • [34] Multigram Scale Synthesis and Anti-Influenza Activity of 3-Indoleacetonitrile Glucosides
    Dong, Jianghong
    Yang, Fengmei
    Li, Shuang
    Li, Zewen
    Qin, Yuanhang
    NATURAL PRODUCT COMMUNICATIONS, 2020, 15 (10)
  • [35] ANTIVIRAL COMPOUNDS .4. SYNTHESIS AND ANTI-INFLUENZA VIRUS ACTIVITY OF AMIDINOHYDRAZONES
    NISHIMURA, T
    YAMAZAKI, C
    TOKU, H
    YOSHII, S
    HASEGAWA, K
    SAITO, M
    NAGAKI, D
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1974, 22 (10) : 2444 - 2447
  • [36] Novel purine conjugates with N-heterocycles: synthesis and anti-influenza activity
    Krasnov, Victor P.
    Zarubaev, Vladimir V.
    Gruzdev, Dmitry A.
    Vozdvizhenskaya, Olga A.
    Vakarov, Sergey A.
    Musiyak, Vera V.
    Chulakov, Evgeny N.
    Volobueva, Alexandrina S.
    Sineguobova, Ekaterina O.
    Ezhikova, Marina A.
    Kodess, Mikhail, I
    Levit, Galina L.
    Charushin, Valery N.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2021, 57 (04) : 498 - 504
  • [37] Design, synthesis and anti-influenza virus activity of furan-substituted spirothiazolidinones
    Apaydin, Cagla Begum
    Tansuyu, Merve
    Cesur, Zafer
    Naesens, Lieve
    Goktas, Fusun
    BIOORGANIC CHEMISTRY, 2021, 112
  • [38] Organic synthesis and anti-influenza A virus activity of cyclobakuchiols A, B, C, and D
    Shoji, Masaki
    Esumi, Tomoyuki
    Tanaka, Narue
    Takeuchi, Misa
    Yamaji, Saki
    Watanabe, Mihiro
    Takahashi, Etsuhisa
    Kido, Hiroshi
    Yamamoto, Masayuki
    Kuzuhara, Takashi
    PLOS ONE, 2021, 16 (03):
  • [39] Novel purine conjugates with N-heterocycles: synthesis and anti-influenza activity
    Victor P. Krasnov
    Vladimir V. Zarubaev
    Dmitry А. Gruzdev
    Olga А. Vozdvizhenskaya
    Sergey А. Vakarov
    Vera V. Musiyak
    Evgeny N. Chulakov
    Alexandrina S. Volobueva
    Ekaterina O. Sinegubova
    Marina А. Ezhikova
    Mikhail I. Kodess
    Galina L. Levit
    Valery N. Charushin
    Chemistry of Heterocyclic Compounds, 2021, 57 : 498 - 504
  • [40] Design, synthesis and biological activity of novel chalcone derivatives as anti-influenza agents
    Fangyuan Shi
    Hao Fang
    Wenfang Xu
    Chemical Research in Chinese Universities, 2016, 32 : 28 - 34