Citric acid, a green catalyst for the one-pot, multi-component synthesis of highly substituted piperidines

被引:0
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作者
Zahra Madanifar
Malek-Taher Maghsoodlou
Mehrnoosh Kangani
Nourallah Hazeri
机构
[1] University of Sistan and Baluchestan,Department of Chemistry
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Citric acid; Green catalyst; Highly substituted piperidines; β-Ketoesters;
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摘要
Citric acid has been used as a green and efficient catalyst for one-pot, multi-component synthesis of highly substituted piperidines by condensation of aromatic aldehydes, aromatic amines, and β-ketoesters in MeOH at ambient temperature. This method has several advantages including use of a nonhazardous and inexpensive catalyst, easy work-up, clean reaction conditions, and high yields.
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页码:9863 / 9869
页数:6
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