Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library

被引：0
|
作者：
Jin Zhou
Geng Bo Chen
Yew Chung Tang
Rohit Anthony Sinha
Yonghui Wu
Chui Sun Yap
Guihua Wang
Junbo Hu
Xianmin Xia
Patrick Tan
Liang Kee Goh
Paul Michael Yen
机构：
[1] Duke-National University of Singapore Graduate Medical School,Laboratory of Hormonal Regulation, Cardiovascular and Metabolic Disorders Program
[2] Cancer and Stem Cell Program,Laboratory of Genomic Oncology
[3] Duke-National University of Singapore Graduate Medical School,Laboratory of Computational Biology
[4] Cancer and Stem Cell Program,Laboratory of Computational Systems Biology and Human Genetics
[5] Duke-National University of Singapore Graduate Medical School,Cancer Research Institute
[6] Neuroscience and Behavioral Disorder Program,Department of Medical Oncology
[7] Duke-National University of Singapore Graduate Medical School,Saw Swee Hock School of Public Health
[8] Tongji Hospital,Cellular and Molecular Research
[9] Huazhong University of Science and Technology,Cancer Science Institute of Singapore
[10] National Cancer Centre,undefined
[11] National University of Singapore,undefined
[12] National Cancer Centre,undefined
[13] National University of Singapore,undefined
[14] Genome Institute of Singapore,undefined
来源：
BMC Medical Genomics | / 5卷
关键词：
Gastric Cancer; Gastric Cancer Cell; Gastric Cancer Cell Line; Gastric Cancer Sample; HGC27 Cell;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Role of the PI3K regulatory subunit in the control of actin organization and cell migration
    Jiménez, C
    Portela, RA
    Mellado, M
    Rodríguez-Frade, JM
    Collard, J
    Serrano, A
    Martínez-A, C
    Avila, J
    Carrera, AC
    JOURNAL OF CELL BIOLOGY, 2000, 151 (02): : 249 - 261
  • [32] Diminished neutrophil responses in mice lacking the regulatory subunit of phosphoinositide 3-hydroxykinase γ (PI3Kγ)
    Condliffe, AM
    Ferguson, GJ
    Chilvers, ER
    Hawkins, PT
    Stephens, LR
    THORAX, 2002, 57
  • [33] Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)
    Ito, Yoshihiro
    Hart, Jonathan R.
    Ueno, Lynn
    Vogt, Peter K.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (47) : 16826 - 16829
  • [34] Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expression
    Xu, Hong-Fa
    Huang, Tie-Jun
    Yang, Qin
    Xu, Liang
    Lin, Fen
    Lang, Yan-Hong
    Hu, Hao
    Peng, Li-Xia
    Meng, Dong-Fang
    Xie, Yu-Jie
    Tan, Li
    Qian, Chao-Nan
    Huang, Bi-Jun
    CANCER MANAGEMENT AND RESEARCH, 2019, 11 : 5557 - 5572
  • [35] Differential expression of PI3K isoforms and correlation with clinicopathological factors in patients with gastric cancer
    Lee, Hyoun Wook
    Lee, Eun Hee
    Park, Moon-il
    Kim, Mee-Seon
    Jeong, Jin Sook
    Roh, Mee Sook
    Kim, Dae Cheol
    Kim, Su Jin
    Pak, Min Gyoung
    Rha, Seo Hee
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2016, 9 (02): : 1588 - 1597
  • [36] MicroRNAs and the PTEN/PI3K/Akt pathway in gastric cancer
    Hu, Mingli
    Zhu, Shixuan
    Xiong, Shengwei
    Xue, Xingxing
    Zhou, Xiaodong
    ONCOLOGY REPORTS, 2019, 41 (03) : 1439 - 1454
  • [37] Comparative molecular dynamics analyses on PIK3CA hotspot mutations with PI3Kα specific inhibitors and ATP
    Mentes, Muratcan
    Karakuzulu, Basak Buse
    Ucar, Gonlum Bahar
    Yandim, Cihangir
    COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2022, 99
  • [38] Differential response to a dual PI3K/mTOR inhibitor in PIK3CA mutant urothelial cancer patient derived xenografts
    Elbanna, May F.
    Ciamporcero, Eric
    Adelaiye, Remi
    Orillion, Ashley
    Chintala, Sreenivasulu
    Pili, Roberto
    CANCER RESEARCH, 2016, 76
  • [39] Role of class IA PI3K in regulatory T cell function
    Fujii, Hideki
    Matsuda, Satoshi
    Ohtani, Masashi
    Koyasu, Shigeo
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [40] Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit
    Shriver, Marey
    Marimuthu, Saravanakumar
    Paul, Colin
    Geist, Janelle
    Seale, Tessa
    Konstantopoulos, Konstantinos
    Kontrogianni-Konstantopoulos, Aikaterini
    ONCOTARGET, 2016, 7 (29) : 45414 - 45428
12345