The Characterization of the Human Nasal Epithelial Cell Line RPMI 2650 Under Different Culture Conditions and Their Optimization for an Appropriate in vitro Nasal Model

被引:0
|
作者
Mateja Erdani Kreft
Urška Dragin Jerman
Eva Lasič
Tea Lanišnik Rižner
Neli Hevir-Kene
Luka Peternel
Katja Kristan
机构
[1] University of Ljubljana,Institute of Cell Biology, Faculty of Medicine
[2] Lek Pharmaceuticals,Institute of Biochemistry, Faculty of Medicine
[3] d.d.,undefined
[4] Sandoz Development Center Slovenia,undefined
[5] University of Ljubljana,undefined
来源
Pharmaceutical Research | 2015年 / 32卷
关键词
drug transporters; microscopy; nasal epithelial cell model; permeability; TEER;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:665 / 679
页数:14
相关论文
共 50 条
  • [11] Comparison of RPMI 2650 cell layers and excised sheep nasal epithelial tissues in terms of nasal drug delivery and immunocytochemistry properties
    Gerber, Werner
    Svitina, Hanna
    Steyn, Dewald
    Peterson, Bianca
    Kotze, Awie
    Weldon, Che
    Hamman, Josias H.
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2022, 113
  • [12] A Modified Cell-Penetrating Peptide Enhances Insulin and Oxytocin Delivery across an RPMI 2650 Nasal Epithelial Cell Barrier In Vitro
    Wong, Sara
    Brown, Alexander D.
    Abrahams, Abigail B.
    Nurzak, An Nisaa
    Eltaher, Hoda M.
    Sykes, David A.
    Veprintsev, Dmitry B.
    Fone, Kevin C. F.
    Dixon, James E.
    King, Madeleine V.
    PHARMACEUTICS, 2024, 16 (10)
  • [13] Evaluation of human nasal RPMI 2650 cells grown at an air-liquid interface as a model for nasal drug transport studies
    Bai, Shuhua
    Yang, Tianzhi
    Abbruscato, Thomas J.
    Ahsan, Fakhrul
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2008, 97 (03) : 1165 - 1178
  • [14] DEVELOPMENT OF A HUMAN NASAL EPITHELIAL-CELL CULTURE MODEL AND ITS SUITABILITY FOR TRANSPORT AND METABOLISM STUDIES UNDER IN-VITRO CONDITIONS
    WERNER, U
    KISSEL, T
    PHARMACEUTICAL RESEARCH, 1995, 12 (04) : 565 - 571
  • [15] Application of RPMI 2650 nasal cell model to a 3D printed apparatus for the testing of drug deposition and permeation of nasal products
    Pozzoli, Michele
    Ong, Hui Xin
    Morgan, Lucy
    Sukkar, Maria
    Traini, Daniela
    Young, Paul M.
    Sonvico, Fabio
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2016, 107 : 223 - 233
  • [16] Development of an in vitro human nasal epithelial (HNE) cell model
    Schmidt, D
    Hubsch, U
    Wurzer, H
    Heppt, W
    Aufderheide, M
    TOXICOLOGY LETTERS, 1996, 88 (1-3) : 75 - 79
  • [17] The characterization of the human cell line Calu-3 under different culture conditions and its use as an optimized in vitro model to investigate bronchial epithelial function
    Kreft, Mateja Erdani
    Jerman, Urska Dragin
    Lasic, Eva
    Hevir-Kene, Neli
    Rizner, Tea Lanisnik
    Peternel, Luka
    Kristan, Katja
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 69 : 1 - 9
  • [19] Nasal delivery of peptides: An in vitro cell culture model for the investigation of transport and metabolism in human nasal epithelium
    Kissel, T
    Werner, U
    JOURNAL OF CONTROLLED RELEASE, 1998, 53 (1-3) : 195 - 203
  • [20] Nasal sprayed particle deposition in a human nasal cavity under different inhalation conditions
    Calmet, Hadrien
    Inthavong, Kiao
    Eguzkitza, Beatriz
    Lehmkuhl, Oriol
    Houzeaux, Guillaume
    Vazquez, Mariano
    PLOS ONE, 2019, 14 (09):