Transition metal-free, base-promoted hydroalkoxylation: Synthesis of substituted imidazo[2,1-c][1,4]oxazines

被引：0
|
作者：
MUTHUPANDI NAGARAJ
SHANMUGAM MUTHUSUBRAMANIAN
机构：
[1] Madurai Kamaraj University,Department of Organic Chemistry, School of Chemistry
来源：
Journal of Chemical Sciences | 2016年 / 128卷
关键词：
1,4-Oxazines; hydroalkoxylation; 6-; regioselectivity; 1,5-alkynyl alcohol;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
An efficient, transition metal-free method to synthesize substituted imidazo[2,1-c][1,4]oxazine derivatives via hydroalkoxylation of 1,5-alkynyl alcohol has been described. The reaction proceeds regioselectively with exclusive formation of 6-exo-dig product.
引用
收藏
页码：451 / 458
页数：7
相关论文
共 50 条
  • [1] Transition metal-free, base-promoted hydroalkoxylation: Synthesis of substituted imidazo[2,1-c][1,4]oxazines
    Nagaraj, Muthupandi
    Muthusubramanian, Shanmugam
    JOURNAL OF CHEMICAL SCIENCES, 2016, 128 (03) : 451 - 458
  • [2] SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF SOME 3-SUBSTITUTED "OCTAHYDROPYRIDO[2,1-C][1,4]OXAZINES
    RILEY, TN
    RANKIN, GO
    JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (02) : 334 - 336
  • [3] REGIOSELECTIVE ELECTROPHILIC SUBSTITUTIONS OF 4H-IMIDAZO[2,1-C][1,4]BENZOXAZINE AND 4H-IMIDAZO[2,1-C][1,4]BENZTHIAZINE
    RAO, KVP
    SUNDARAMURTHY, V
    JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (09): : 2737 - 2739
  • [4] A FACILE SYNTHESIS OF "4H-IMIDAZO-[2,1-C][1,4]BENZOXAZINES
    RAO, KVP
    REDDY, PSN
    SUNDARAMURTHY, V
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1985, 24 (11): : 1120 - 1123
  • [5] Chemistry of pyrido[2,1-c][1,4]oxazines, pyrido[2,1-c][1,4]thiazines, pyrido[1,2-a]pyrazines and their benzologues
    Hermecz, I
    ADVANCES IN HETEROCYCLIC CHEMISTRY, VOL 71, 1998, 71 : 145 - 289
  • [6] SYNTHESIS OF NOVEL IMIDAZO[1,2-A]PYRROLO[2,1-C][1,4]BENZODIAZEPINES AND PYRIMIDO[1,2-A]PYRROLO[2,1-C][1,4]BENZODIAZEPINES
    DUCEPPE, JS
    GAUTHIER, J
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1985, 22 (02) : 305 - 310
  • [7] Base-promoted synthesis of dibenzoxazepinamines and quinazolinimines under metal-free conditions
    Feng, Jian-Bo
    Wu, Xiao-Feng
    GREEN CHEMISTRY, 2015, 17 (09) : 4522 - 4526
  • [8] Transition metal-free base-promoted arylation of sulfenate anions with diaryliodonium salts
    Wang, Lei
    Chen, Mingjie
    Zhang, Junliang
    ORGANIC CHEMISTRY FRONTIERS, 2019, 6 (01): : 32 - 35
  • [9] PYRROLO[2,1-C][1,4]BENZODIAZEPINES - SYNTHESIS OF N-SUBSTITUTED AMIDINES
    FOLOPPE, MP
    RAULT, I
    RAULT, S
    ROBBA, M
    HETEROCYCLES, 1993, 36 (01) : 63 - 69
  • [10] SYNTHESIS AND ANTHELMINTIC ACTIVITY OF SOME METHYL H-4-IMIDAZO-[2,1-C][1,4]BENZOXAZINE-2-CARBAMATES AND METHYL H-4-IMIDAZO[2,1-C][1,4]BENZOTHIA-ZINE-2-CARBAMATES
    SHRIDHAR, DR
    JOGIBHUKTA, M
    KRISHNAN, VSH
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1982, 21 (02): : 130 - 133
12345