The efficacy and safety of deucravacitinib compared to methotrexate, in patients with vulvar lichen planus who have failed topical therapy with potent corticosteroids: a study protocol for a single-centre double-blinded randomised controlled trial

被引：0
|
作者：
Marlene Wijaya
Gayle Fischer
Rebecca Bronwyn Saunderson
机构：
[1] Royal North Shore Hospital,Department of Dermatology
[2] The University of Sydney,undefined
[3] Northern Clinical School,undefined
来源：
Trials | / 25卷
关键词：
Vulvar lichen planus; Deucravacitinib; Methotrexate; Randomised clinical trial;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Effectiveness and safety of mesenchymal stem/stromal cell for radiation-induced hyposalivation and xerostomia in previous head and neck cancer patients (MESRIX-III): a study protocol for a single-centre, double-blinded, randomised, placebo-controlled, phase II study
    Kathrine Kronberg Jakobsen
    Amanda-Louise Fenger Carlander
    Christian Grønhøj
    Tobias Todsen
    Jacob Melchiors
    Natasja Paaske
    Anne Kathrine Østergaard Madsen
    Jens Kastrup
    Annette Ekblond
    Mandana Haack-Sørensen
    Mohammad Farhadi
    Christian Maare
    Jeppe Friborg
    Charlotte Duch Lynggard
    Christian von Buchwald
    Trials, 24
  • [32] Correction: Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy
    Alaa Abouhajar
    Lisa Alcock
    Theophile Bigirumurame
    Penny Bradley
    Laura Brown
    Ian Campbell
    Silvia Del Din
    Julie Faitg
    Gavin Falkous
    Grainne S. Gorman
    Rachel Lakey
    Robert McFarland
    Jane Newman
    Lynn Rochester
    Vicky Ryan
    Hesther Smith
    Alison Steel
    Renae J. Stefanetti
    Huizhong Su
    Robert W. Taylor
    Naomi J. P. Thomas
    Helen Tuppen
    Amy E. Vincent
    Charlotte Warren
    Gillian Watson
    Trials, 23
  • [33] Rationale and design for the thoracic Paravertebral Adjunctive Dexamethasone Palmitate Reducing chronic pain After cardiac surgery (PANDORA) trial: a parallel-group, double-blinded, randomised controlled, single-centre study
    Zhang, Hui
    Zhang, Taoyuan
    Zheng, Ziyu
    Gao, Jiao
    Gao, Baobao
    Hou, Lihong
    Zhao, Jing
    Wang, Lini
    Dong, Hailong
    Lei, Chong
    BMJ OPEN, 2025, 15 (01):
  • [34] Effectiveness of the KC@H programme compared with clinic-based rehabilitation in patients recovering from ACL reconstruction: a study protocol for a single-centre, two-arm, single-blinded, randomised controlled superiority trial
    Alegrete, Joana
    Batalha, Nuno
    Fernandes, Orlando
    Parraca, Jose Alberto
    Rodrigues, Ana Maria
    Londral, Ana Rita
    Sousa, Joao Paulo
    BMJ OPEN SPORT & EXERCISE MEDICINE, 2024, 10 (01):
  • [35] Generate-Boost: study protocol for a prospective, multicenter, randomized controlled, double-blinded phase II trial to evaluate efficacy and safety of bortezomib in patients with severe autoimmune encephalitis
    Jonathan Wickel
    Ha-Yeun Chung
    Stephanie Platzer
    Thomas Lehmann
    Harald Prüss
    Frank Leypoldt
    Albrecht Günther
    André Scherag
    Christian Geis
    Trials, 21
  • [36] Generate-Boost: study protocol for a prospective, multicenter, randomized controlled, double-blinded phase II trial to evaluate efficacy and safety of bortezomib in patients with severe autoimmune encephalitis
    Wickel, Jonathan
    Chung, Ha-Yeun
    Platzer, Stephanie
    Lehmann, Thomas
    Pruess, Harald
    Leypoldt, Frank
    Guenther, Albrecht
    Scherag, Andre
    Geis, Christian
    TRIALS, 2020, 21 (01)
  • [37] Intravenous magnesium sulphate as an adjuvant therapy in acute exacerbations of chronic obstructive pulmonary disease: a single centre, randomised, double-blinded, parallel group, placebo-controlled trial: a pilot study
    Mukerji, S.
    Shahpuri, B.
    Clayton-Smith, B.
    Smith, N.
    Armstrong, P.
    Hardy, M.
    Marchant, G.
    Marsh, E.
    NEW ZEALAND MEDICAL JOURNAL, 2015, 128 (1425) : 34 - 42
  • [38] Efficacy and safety of adalimumab for inflammatory flare prevention in paediatric non-infectious anterior uveitis with peripheral retinal vascular leakage: a study protocol for a single-centre, randomised controlled trial
    Song, Hang
    Zhao, Chan
    Zhang, Yuelun
    Li, Donghui
    Qian, Yujing
    Gao, Fei
    Xiao, Junyan
    Zhang, Meifen
    BMJ OPEN, 2022, 12 (12): : e062211
  • [39] Efficacy and safety of guselkumab in biologic-naive patients with active axial psoriatic arthritis: study protocol for STAR, a phase 4, randomized, double-blinded, placebo-controlled trial
    Gladman, Dafna D.
    Mease, Philip J.
    Bird, Paul
    Soriano, Enrique R.
    Chakravarty, Soumya D.
    Shawi, May
    Xu, Stephen
    Quinn, Sean T.
    Gong, Cinty
    Leibowitz, Evan
    Poddubnyy, Denis
    Tam, Lai-Shan
    Helliwell, Philip S.
    Kavanaugh, Arthur
    Deodhar, Atul
    Ostergaard, Mikkel
    Baraliakos, Xenofon
    TRIALS, 2022, 23 (01)
  • [40] Comparison of the efficacy and safety of leflunomide versus placebo combined with basic prednisone therapy in patients with active disease phase of Takayasu arteritis: study protocol for a randomized, double-blinded controlled trial (Takayasu arteritis clinical trial in China: TACTIC)
    Sun, Ying
    Wu, Bingjie
    Zhang, Wei
    Ma, Lili
    Kong, Xiufang
    Chen, Huiyong
    Jiang, Lindi
    THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2023, 14
12345