Type VII secretion systems: Targets against tuberculosis

被引：0
|
作者：
Geibel S. [1 ]
机构：
[1] Leiden Institute of Chemistry, Universität Leiden, Gorlaeus Building, Leiden
来源：
BIOspektrum | 2022年 / 28卷 / 2期
关键词：
D O I：
10.1007/s12268-022-1713-x
中图分类号：
学科分类号：
摘要：
To facilitate host infection, tuberculosis-causing mycobacteria employ five type VII secretion systems (T7SS) to orchestrate the timely secretion of effector proteins, which play central roles in their immune evasion strategy and ensure the uptake of essential nutrients. This article reviews our current structural and functional understanding of mycobacterial T7SS and discusses their potential as targets for novel antimicrobial strategies. © 2022, Der Autor.
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页码：128 / 131
页数：3
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