Synthesis and Antibacterial Activity of 1-[2-(4-Aminosulfonylphenyl)Ethyl]-5-Aryl-4-Aroyl-3-Hydroxy-3-Pyrrolin-2-Ones

被引：0
|
作者：
V. L. Gein
O. V. Bobrovskaya
R. T. Valiev
T. F. Odegova
G. A. Gartman
机构：
[1] Ministry of Health of the Russian Federation,Perm State Pharmaceutical Academy
[2] Perm State National Research University,undefined
来源：
Pharmaceutical Chemistry Journal | 2015年 / 49卷
关键词：
1-[2-(4-aminosulfonylphenyl)ethyl]-5-aryl-4-aroyl-3-hydroxy-3-pyrrolin-2-ones; synthesis; antibacterial activity;
D O I：
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学科分类号：
摘要：
Reaction of the methyl esters of aroylpyruvic acids with mixtures of 4-(2-aminoethyl)benzenesulfonamide and an aromatic aldehyde was used to synthesize 1-[2-(4-aminosulfonylphenyl)ethyl]-5-aryl-4-aroyl-3-hydroxy- 3-pyrrolin-2-ones. The structures of these compounds were verified by IR and 1H NMR spectroscopy and mass spectrometry. Their antibacterial activity was studied.
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页码：602 / 604
页数：2
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