New insights into targeted therapy of glioblastoma using smart nanoparticles

被引：4
|
作者：
Ghaznavi, Habib [1 ]
Afzalipour, Reza [2 ,3 ]
Khoei, Samideh [4 ]
Sargazi, Saman [5 ,6 ]
Shirvalilou, Sakine [4 ]
Sheervalilou, Roghayeh [1 ]
机构：
[1] Zahedan Univ Med Sci, Pharmacol Res Ctr, Zahedan, Iran
[2] Hormozgan Univ Med Sci, Hormozgan Hlth Inst, Mol Med Res Ctr, Bandar Abbas, Iran
[3] Hormozgan Univ Med Sci, Fac Paramed, Dept Radiol, Bandar Abbas, Iran
[4] Iran Univ Med Sci, Finetech Med Res Ctr, Sch Med, Dept Med Phys, Box 1449614525, Tehran, Iran
[5] Zahedan Univ Med Sci, Res Inst Cellular & Mol Sci Infect Dis, Cellular & Mol Res Ctr, Zahedan, Iran
[6] Zahedan Univ Med Sci, Sch Med, Dept Clin Biochem, Zahedan, Iran
来源：
CANCER CELL INTERNATIONAL | 2024年 / 24卷 / 01期
关键词：
Smart nanoparticles; Glioblastoma (GBM); Therapy; Clinical trials; IRON-OXIDE NANOPARTICLES; CENTRAL-NERVOUS-SYSTEM; MAGNETIC NANOPARTICLES; PHOTOTHERMAL THERAPY; GOLD NANOPARTICLES; DRUG-DELIVERY; RADIOTHERAPY-TEMOZOLOMIDE; MULTIFORME TREATMENT; COMBINATION THERAPY; GENE DELIVERY;
D O I：
10.1186/s12935-024-03331-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In recent times, the intersection of nanotechnology and biomedical research has given rise to nanobiomedicine, a captivating realm that holds immense promise for revolutionizing diagnostic and therapeutic approaches in the field of cancer. This innovative fusion of biology, medicine, and nanotechnology aims to create diagnostic and therapeutic agents with enhanced safety and efficacy, particularly in the realm of theranostics for various malignancies. Diverse inorganic, organic, and hybrid organic-inorganic nanoparticles, each possessing unique properties, have been introduced into this domain. This review seeks to highlight the latest strides in targeted glioblastoma therapy by focusing on the application of inorganic smart nanoparticles. Beyond exploring the general role of nanotechnology in medical applications, this review delves into groundbreaking strategies for glioblastoma treatment, showcasing the potential of smart nanoparticles through in vitro studies, in vivo investigations, and ongoing clinical trials.
引用
收藏
页数：18
相关论文
共 50 条
  • [31] The use of myristic acid as a ligand of polyethylenimine/DNA nanoparticles for targeted gene therapy of glioblastoma
    Li, Jin
    Gu, Bing
    Meng, Qinggang
    Yan, Zhiqiang
    Gao, Huile
    Chen, Xishan
    Yang, Xiangkun
    Lu, Weiyue
    NANOTECHNOLOGY, 2011, 22 (43)
  • [32] DEVELOPMENT OF TARGETED NANOMEDICINE FOR GLIOBLASTOMA THERAPY
    Setua, S.
    Watts, C.
    Welland, M.
    NEURO-ONCOLOGY, 2012, 14 : 88 - 89
  • [33] Recent advances in targeted therapy for glioblastoma
    Mittal, Shivani
    Pradhan, Shrikant
    Srivastava, Tapasya
    EXPERT REVIEW OF NEUROTHERAPEUTICS, 2015, 15 (08) : 935 - 946
  • [34] Targeted therapy in glioblastoma: update and perspectives
    Idbaih, Ahmed
    Duran-Pena, Alberto
    Alentorn, Agusti
    BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 2015, 199 (8-9): : 1323 - 1329
  • [35] The Woman's Heart: Insights into New Potential Targeted Therapy
    Gianfrilli, Daniele
    Pofi, Ricardo
    Feola, Tiziana
    Lenzi, Andrea
    Giannetta, Elisa
    CURRENT MEDICINAL CHEMISTRY, 2017, 24 (24) : 2650 - 2660
  • [36] Fenofibrate triggers apoptosis of glioblastoma cells in vitro: New insights for therapy
    Giordano, Antonio
    Macaluso, Marcella
    CELL CYCLE, 2012, 11 (17) : 3154 - 3154
  • [37] Cilengitide: Does It Really Represent a New Targeted Therapy for Recurrent Glioblastoma? Reply
    Reardon, David A.
    JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (11) : 1922 - 1922
  • [38] Targeted and Synergic Glioblastoma Treatment: Multifunctional Nanoparticles Delivering Verteporfin as Adjuvant Therapy for Temozolomide Chemotherapy
    Pellosi, Diogo S.
    Paula, Leonardo B.
    de Melo, Maryanne T.
    Tedesco, Antonio C.
    MOLECULAR PHARMACEUTICS, 2019, 16 (03) : 1009 - 1024
  • [39] Targeted delivery of gold nanoparticles by neural stem cells to glioblastoma for enhanced radiation therapy: a review
    Sababathy, Mogesh
    Ramanathan, Ghayathri
    Tan, Suat Cheng
    AIMS NEUROSCIENCE, 2022, 9 (03) : 303 - 319
  • [40] CD38-TARGETED THERAPY IN GLIOBLASTOMA
    Aulakh, Sonikpreet
    Manna, Alak
    Schiapparelli, Paula
    Ailawadhi, Sikander
    Paulus, Aneel
    Rosenfeld, Steven
    Quinones-Hinojosa, Alfredo
    Chanan-Khan, Asher
    NEURO-ONCOLOGY, 2018, 20 : 86 - 86
12345