Tubular toxicity of proteinuria

被引:0
|
作者
Richard J. Baines
Nigel J. Brunskill
机构
[1] Immunity and Inflammation,Department of Infection
[2] University of Leicester,undefined
来源
Nature Reviews Nephrology | 2011年 / 7卷
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摘要
Proteinuria is a prognostic indicator of renal function loss, and understanding the mechanisms underlying proteinuric nephropathy is a topic of intense interest. In this Perspectives article, Richard Baines and Nigel Brunskill consider the importance of megalin, cubilin, and other receptors in the handling of filtered proteins by PTECs and describe how these factors could contribute to the development of proteinuric nephropathy.
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页码:177 / 180
页数:3
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