Cox Regression with Covariates Missing Not at Random

被引:8
|
作者
Cook V.J. [1 ]
Hu X.J. [2 ]
Swartz T.B. [2 ]
机构
[1] BC Centre for Disease Control, University of British Columbia, Vancouver, British Columbia V5Z 4R4
[2] Department of Statistics and Acturial Sciences, Simon Fraser University, Burnaby
基金
加拿大自然科学与工程研究理事会;
关键词
Event time; Missing data; Semiparametric estimation; Sensitivity analysis; Supplementary information;
D O I
10.1007/s12561-010-9031-0
中图分类号
学科分类号
摘要
This paper considers estimation under the Cox proportional hazards model with right-censored event times in the presence of covariates missing not at random (MNAR). We propose an approach derived from likelihood estimation utilizing supplementary information. We show that available additional information not only helps to account appropriately for the missing covariates but also leads to estimation procedures which are natural and easy to implement. A medical example is used throughout the paper to motivate the problem and to illustrate the proposed methodology. © 2010 International Chinese Statistical Association.
引用
收藏
页码:208 / 222
页数:14
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