Intimate details of the most poisonous poison

被引：0
|
作者：
Bal Ram Singh
机构：
[1] University of Massachusetts Dartmouth,the Department of Chemistry and Biochemistry
来源：
Nature Structural Biology | 2000年 / 7卷
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摘要：
Crystal structures of type B botulinum neurotoxin, determined under conditions relevant to the extracellular binding and intracellular substrate cleavage steps of its toxic action, reveal that minimal structural changes occur upon binding a ganglioside or after substrate cleavage. The unique structure of this toxin provides information for developing preventive measures against botulism.
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页码：617 / 619
页数：2
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