miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure

被引：0
|
作者：
Qingxi Qu
Linghong Liu
Yuqian Cui
Hongli Liu
Jingyang Yi
Weidong Bing
Chunxiao Liu
Detian Jiang
Yanwen Bi
机构：
[1] Qilu Hospital of Shandong University,Department of Obstetrics and Gynecology
[2] Shandong University,Research Center of Stem Cell and Regenerative Medicine
[3] Qilu Hospital of Shandong University,Laboratory of Cryomedicine
[4] Christchurch Hospital,Otago Medical School
[5] University of Otago,Department of Cardiovascular Surgery
[6] Qilu Hospital of Shandong University,undefined
来源：
Stem Cell Research & Therapy | / 13卷
关键词：
Exosomes; Mesenchymal stem cells; Granulosa cell; Angiogenesis; Apoptosis; Premature ovarian insufficiency;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Clusterin-carrying extracellular vesicles derived from human umbilical cord mesenchymal stem cells restore the ovarian function of premature ovarian failure mice through activating the PI3K/AKT pathway
    He, Jing
    Ao, Chunchun
    Li, Mao
    Deng, Taoran
    Zheng, Shuo
    Zhang, Ke
    Tu, Chengshu
    Ouyang, Yu
    Lang, Ruibo
    Jiang, Yijia
    Yang, Yifan
    Li, Changyong
    Wu, Dongcheng
    STEM CELL RESEARCH & THERAPY, 2024, 15 (01)
  • [42] Exosomes secreted from human umbilical cord mesenchymal stem cells promote pancreatic ductal adenocarcinoma growth by transferring miR-100-5p
    Ding, Yixuan
    Mei, Wentong
    Zheng, Zhi
    Cao, Feng
    Liang, Kuo
    Jia, Yuchen
    Wang, Yuting
    Liu, Dachuan
    Li, Jia
    Li, Fei
    TISSUE & CELL, 2021, 73
  • [43] Umbilical cord blood mesenchymal stem cell-derived conditioned medium induces the apoptosis and autophagy of ovarian cancer SKOV3 cells
    Hua, Q.
    Sun, L.
    Li, H. R.
    Li, H. J.
    Ma, B. D.
    Wang, Y. L.
    JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 2021, 35 (05): : 1631 - 1638
  • [44] Fabrication of hydroxyapatite/chitosan composite hydrogels loaded with exosomes derived from miR-126-3p overexpressed synovial mesenchymal stem cells for diabetic chronic wound healing
    Li, Min
    Ke, Qin-Fei
    Tao, Shi-Cong
    Guo, Shang-Chun
    Rui, Bi-Yu
    Guo, Ya-Ping
    JOURNAL OF MATERIALS CHEMISTRY B, 2016, 4 (42) : 6830 - 6841
  • [45] Human Amniotic Fluid Mesenchymal Stem Cell-Derived Exosomes Inhibit Apoptosis in Ovarian Granulosa Cell via miR-369-3p/YAF2/PDCD5/p53 Pathway
    Geng, Zixiang
    Chen, Haiyang
    Zou, Gang
    Yuan, Long
    Liu, Peng
    Li, Bingrong
    Zhang, Kaiyong
    Jing, Fangyuan
    Nie, Xiaoli
    Liu, Te
    Zhang, Bimeng
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2022, 2022
  • [46] Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Attenuate Myocardial Infarction Injury via miR-24-3p-Promoted M2 Macrophage Polarization
    Zhu, Feng
    Chen, Yihuan
    Li, Jingjing
    Yang, Ziying
    Lin, Yang
    Jiang, Boxuan
    Shao, Lianbo
    Hu, Shengshou
    Shen, Zhenya
    ADVANCED BIOLOGY, 2022, 6 (11):
  • [47] Effects of miR-214-5p and miR-21-5p in hypoxic endometrial epithelial-cell-derived exosomes on human umbilical cord mesenchymal stem cells
    Zhang, Wan-Yu
    Wang, Han-Bi
    Deng, Cheng-Yan
    WORLD JOURNAL OF STEM CELLS, 2024, 16 (11):
  • [48] Effect of preconditioning of human umbilical cord mesenchymal stem cells with hydrogen peroxide on the therapeutic potential of MSCs in the cyclophosphamide-induced premature ovarian failure mice model
    Jalali, Ladan
    Allahveisie, Azra
    Rezaei, Shohreh
    Ravanyar, Leila
    Kiasatfar, Jafar
    Rezaie, Mohammad-Jafar
    Raoo, Amir
    TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, 2023, 62 (05): : 667 - 676
  • [49] Exosomes derived from mesenchymal stem cells attenuate diabetic kidney disease by inhibiting cell apoptosis and epithelial-to-mesenchymal transition via miR-424-5p
    Cui, Chen
    Zang, Nan
    Song, Jia
    Guo, Xinghong
    He, Qin
    Hu, Huiqing
    Yang, Mengmeng
    Wang, Yuanqi
    Yang, Jingwen
    Zou, Ying
    Gao, Jing
    Wang, Lingshu
    Wang, Chuan
    Liu, Fuqiang
    He, Falian
    Hou, Xinguo
    Chen, Li
    FASEB JOURNAL, 2022, 36 (10):
  • [50] Microvesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance Alveolar Type II Cell Proliferation and Attenuate Lung Inflammation in a Rat Model of Bronchopulmonary Dysplasia
    Zhou, Ou
    You, Jingyi
    Xu, Xiaochuan
    Liu, Jiang
    Qiu, Huijun
    Hao, Chang
    Zou, Wenjing
    Wu, Wenjie
    Fu, Zhou
    Tian, Daiyin
    Zou, Lin
    STEM CELLS INTERNATIONAL, 2022, 2022
12345