FOXA1 and breast cancer risk

被引：0
|
作者：
Kerstin B Meyer
Jason S Carroll
机构：
[1] Kerstin B. Meyer and Jason S. Carroll are at Cancer Research UK,and the Department of Oncology
[2] Cambridge,undefined
[3] UK,undefined
[4] University of Cambridge,undefined
[5] Cambridge,undefined
[6] UK.,undefined
来源：
Nature Genetics | 2012年 / 44卷
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摘要：
Many SNPs associated with human disease are located in non-coding regions of the genome. A new study shows that SNPs associated with breast cancer risk are located in enhancer regions and alter binding affinity for the pioneer factor FOXA1.
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页码：1176 / 1177
页数：1
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