Platelet-derived growth factor in human brain tumors

被引：0

作者：

Matthias Kirsch

John C. Wilson

and Peter Black

机构：

[1] Neurosurgical Laboratories and Brain Tumor Center,Klinik und Poliklinik für Neurochirurgie

[2] Carl-Gustav-Carus Universitätsklinikum,Women‘s Hospital, Children‘s Hospital, Dana

[3] Technische Universität,Farber Cancer Institute, Joint Center for Radiation Therapy, Department of Surgery

[4] Harvard Medical School,undefined

来源：

Journal of Neuro-Oncology | 1997年 / 35卷

关键词：

Public Health; Growth Factor; Receptor Antagonist; Brain Tumor; Human Brain;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

This paper initially reviews ligand and receptor systemsfor the PDGF family and the signalling systemsthey use as well as their role inneural developments. It then describes the putative roleof this family in astrocytoma, meningioma, and pituitaryadenoma pathogenesis. Potential therapies with receptor antagonists ordominant negative mutants are discussed in the finalsections.

引用

页码：289 / 301

页数：12

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