Purpose. The purpose of this work was to construct and characterize a new potent hFIX plasmid, p2SV-hFIX, which has two hFIX expression units containing the SV40 promoter/enhancer for hemophilia B gene therapy.
机构:
Indiana Univ Sch Med, Herman B Wells Ctr Pediat Res, Indianapolis, IN 46202 USAIndiana Univ Sch Med, Herman B Wells Ctr Pediat Res, Indianapolis, IN 46202 USA
机构:
Jichi Med Univ, Res Div Cell & Mol Med, Ctr Mol Med, Shimotsuke, Tochigi 3290498, JapanJichi Med Univ, Res Div Cell & Mol Med, Ctr Mol Med, Shimotsuke, Tochigi 3290498, Japan
Ohmori, T.
Mizukami, H.
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Jichi Med Univ, Ctr Mol Med, Div Genet Therapeut, Shimotsuke, Tochigi 3290498, JapanJichi Med Univ, Res Div Cell & Mol Med, Ctr Mol Med, Shimotsuke, Tochigi 3290498, Japan
Mizukami, H.
Ozawa, K.
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Univ Tokyo, Inst Med Sci, Tokyo, JapanJichi Med Univ, Res Div Cell & Mol Med, Ctr Mol Med, Shimotsuke, Tochigi 3290498, Japan
Ozawa, K.
Sakata, Y.
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Jichi Med Univ, Res Div Cell & Mol Med, Ctr Mol Med, Shimotsuke, Tochigi 3290498, JapanJichi Med Univ, Res Div Cell & Mol Med, Ctr Mol Med, Shimotsuke, Tochigi 3290498, Japan