Reengineering anthrax toxin protective antigen for improved receptor-specific protein delivery

被引：0
|
作者：
Lukas Becker
Wouter P. R. Verdurmen
Andreas Plückthun
机构：
[1] University of Zurich,Department of Biochemistry
[2] Radboud Institute for Molecular Life Sciences (RIMLS),Department of Biochemistry
[3] Radboud University Medical Center,undefined
来源：
BMC Biology | / 18卷
关键词：
Anthrax toxin; Protective antigen; Cytosolic protein delivery; DARPin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Lethal factor of anthrax toxin binds monomeric form of protective antigen
    Chvyrkova, Irina
    Zhang, Xuejun C.
    Terzyan, Simon
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 360 (03) : 690 - 695
  • [32] Atomic structure of anthrax protective antigen pore elucidates toxin translocation
    Jiansen Jiang
    Bradley L. Pentelute
    R. John Collier
    Z. Hong Zhou
    Nature, 2015, 521 : 545 - 549
  • [33] EMILINs interact with anthrax protective antigen and inhibit toxin action in vitro
    Doliana, Roberto
    Veljkovic, Veljko
    Prljic, Jelena
    Veljkovic, Nevena
    De Lorenzo, Elisa
    Mongiat, Maurizio
    Ligresti, Giovanni
    Marastoni, Stefano
    Colombatti, Alfonso
    MATRIX BIOLOGY, 2008, 27 (02) : 96 - 106
  • [34] The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes
    Kintzer, Alexander F.
    Thoren, Katie L.
    Sterling, Harry J.
    Dong, Ken C.
    Feld, Geoffrey K.
    Tang, Iok I.
    Zhang, Teri T.
    Williams, Evan R.
    Berger, James M.
    Krantz, Bryan A.
    JOURNAL OF MOLECULAR BIOLOGY, 2009, 392 (03) : 614 - 629
  • [35] Alternate clamped states of the anthrax toxin protective antigen channel REPLY
    Krantz, Bryan A.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (13) : E2547 - E2547
  • [36] Molecular dynamics simulations of complexes between wild-type and mutant anthrax protective antigen variants and a model anthrax toxin receptor
    Stiles, L
    Nelson, DJ
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2005, 22 (05): : 503 - 519
  • [37] Electrostatic Ratchet in the Protective Antigen Channel Promotes Anthrax Toxin Translocation
    Wynia-Smith, Sarah L.
    Brown, Michael J.
    Chirichella, Gina
    Kemalyan, Gigi
    Krantz, Bryan A.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (52) : 43753 - 43764
  • [38] Affinity binding of antibodies to supermacroporous cryogel adsorbents with immobilized protein A for removal of anthrax toxin protective antigen
    Ingavle, Ganesh C.
    Baillie, Les W. J.
    Zheng, Yishan
    Lis, Elzbieta K.
    Savina, Irina N.
    Howell, Carol A.
    Mikhalovsky, Sergey V.
    Sandeman, Susan R.
    BIOMATERIALS, 2015, 50 : 140 - 153
  • [39] ANTHRAX PROTECTIVE ANTIGEN INTERACTS WITH A SPECIFIC RECEPTOR ON THE SURFACE OF CHO-K1 CELLS
    ESCUYER, V
    COLLIER, RJ
    INFECTION AND IMMUNITY, 1991, 59 (10) : 3381 - 3386
  • [40] Identification and Characterization of Receptor-Specific Peptides for siRNA Delivery
    Ren, Yin
    Hauert, Sabine
    Lo, Justin H.
    Bhatia, Sangeeta N.
    ACS NANO, 2012, 6 (10) : 8620 - 8631
12345