Antioxidant effect ofPhyllanthus emblica fruits on healing of indomethacin induced gastric ulcer in rats

被引：8
|
作者：
Anita Pakrashi
Srikanta Pandit
Sandip K. Bandyopadhyay
Satyesh C. Pakrashi
机构：
[1] Indian Institute of Chemical Biology,Department of Biochemistry
[2] Calcutta University,University College of Medicine Dr. B. C. Roy Post Graduate Institute of Basic Medical Sciences
来源：
Indian Journal of Clinical Biochemistry | 2003年 / 18卷 / 1期
关键词：
Antioxidant; antiulcer; healing;
D O I：
10.1007/BF02867660
中图分类号：
学科分类号：
摘要：
Post-treatment of the indomethacin induced ulcerated rats at the optimal dose of 100 mg/kg body-wt. orally for 7 consecutive days with the lyophilized aqueous extract of the fruits ofPhyllanthus emblica L. syn.Emblica officinalis Gaertn. (Euphorbiaceae) exhibited highly significant (p<0.001) enhancement of secretion of catalase, reduced glutathione and decrease in malonyldialdehyde (MDA). Furthermore, the gross morphological observation and highly significant (p<0.001) decrease of ulcer index (81.43%) indicated healing effect of the extract on gastric ulcer.
引用
收藏
页码：15 / 21
页数：6
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