Tumour-regulated anorexia preceding cachexia

被引:0
|
作者
Gang Wang
Haiying Zhang
David Lyden
机构
[1] Weill Cornell Medicine,Children’s Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children’s Health, Meyer Cancer Center
来源
Nature Cell Biology | 2021年 / 23卷
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摘要
Anorexia commonly develops in patients with advanced cancer and is closely associated with cachexia. A new study shows that anorexia emerges earlier than cachexia in both Drosophila and mouse tumour models and that tumour-derived humoral factors induce anorexia by systemically dysregulating neuropeptides in the brain.
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页码:111 / 113
页数:2
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