Downregulation of Kcnq1ot1 attenuates β-cell proliferation and insulin secretion via the miR-15b-5p/Ccnd1 and Ccnd2 axis

被引：0
|
作者：
Yanli Li
Yalan Chen
Ziyu Liu
Beisi Lin
Xiaoyi Deng
Qiwen Xiao
Zhishan Chen
Huiyu Ye
Danrui Chen
Yanna Su
Wangen Li
Wen Xu
机构：
[1] The Second Affiliated Hospital of Guangzhou Medical University,Department of Endocrinology
[2] The Third Affiliated Hospital of Sun Yat-Sen University,Key Laboratory of Diabetology of Guangdong Province, Department of Endocrinology and Metabolism
[3] The Second Affiliated Hospital of Guangzhou Medical University,Department of Clinical Laboratory
来源：
Acta Diabetologica | 2022年 / 59卷
关键词：
Kcnq1ot1; miR-15b-5p; Pancreatic ; -cell; Proliferation; Insulin; Diabetes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：885 / 899
页数：14
相关论文
共 50 条
  • [41] Circular RNA RHOT1 Regulates miR-142-5p/CCND1 to Participate in Chondrocyte Autophagy and Proliferation in Osteoarthritis
    Man, Gu
    Yang, Haiwen
    Shen, Kai
    Zhang, Donghong
    Zhang, Julin
    Wu, Hao
    Zhang, Hongyu
    Wang, Jinhuan
    JOURNAL OF IMMUNOLOGY RESEARCH, 2022, 2022
  • [42] LncRNA KCNQ1OT1 attenuates myocardial injury induced by hip fracture via regulating of miR-224-3p/GATA4 axis
    Duan, Xuzhou
    Miao, Zhijing
    Chen, Jia
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2022, 107
  • [43] KCNQ1OT1 affects cell proliferation, invasion, and migration through a miR-34a/Notch3 axis in breast cancer
    Ren, Zhiyao
    Xu, Yunfeng
    Wang, Xin
    Ren, Min
    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2022, 29 (19) : 28480 - 28494
  • [44] Tumor Cell-Derived Exosomal circ-PRKCI Promotes Proliferation of Renal Cell Carcinoma via Regulating miR-545-3p/CCND1 Axis
    Qian, Yiguan
    Li, Yang
    Xu, Luwei
    Chen, Ke
    Liu, Ning
    Yang, Xiaobing
    Lv, Qian
    Li, Rongfei
    Zhou, Changcheng
    Xu, Zheng
    Jia, Ruipeng
    Ge, Yu-Zheng
    CANCERS, 2023, 15 (01)
  • [45] KCNQ1OT1 affects cell proliferation, invasion, and migration through a miR-34a / Notch3 axis in breast cancer
    Zhiyao Ren
    Yunfeng Xu
    Xin Wang
    Min Ren
    Environmental Science and Pollution Research, 2022, 29 : 28480 - 28494
  • [46] LncRNA KCNQ1OT1 enhances the radioresistance of lung squamous cell carcinoma by targeting the miR-491-5p/TPX2-RNF2 axis
    Liu, Jiahui
    Jiang, Mi
    Guan, Jinlei
    Wang, Yuan
    Yu, Wenjuan
    Hu, Yuanping
    Zhang, Xin
    Yang, Jie
    JOURNAL OF THORACIC DISEASE, 2022, : 4081 - 4095
  • [47] Paeoniflorin Sensitizes Breast Cancer Cells to Tamoxifen by Downregulating microRNA-15b via the FOXO1/CCND1/β-Catenin Axis
    Wang, Yanhong
    Wang, Qian
    Li, Xibei
    Luo, Gongwen
    Shen, Mou
    Shi, Jia
    Wang, Xueliang
    Tang, Lu
    DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 15 : 245 - 257
  • [48] LncRNA KCNQ1OT1 accelerates fracture healing via modulating miR-701-3p/FGFR3 axis
    Chen, Lang
    Xiong, Yuan
    Yan, Chenchen
    Zhou, Wu
    Endo, Yori
    Xue, Hang
    Hu, Yiqiang
    Hu, Liangcong
    Leng, Xingzhu
    Liu, Jing
    Lin, Ze
    Mi, Bobin
    Liu, Guohui
    FASEB JOURNAL, 2020, 34 (04): : 5208 - 5222
  • [49] LNCRNA KCNQ1OT1 Promotes Cisplatin Resistance of Osteosarcoma Cancer Cells through miR-335-5p/β-Catenin Axis
    Yang, C.
    Wang, S.
    PEDIATRIC BLOOD & CANCER, 2020, 67 : S186 - S186
  • [50] Long non-coding RNA KCNQ1 opposite transcript 1 (KCNQ1OT1) regulates cell proliferation and invasion via targeting miR-124-3p in gastric carcinoma
    Ye, Xinying
    Liu, Hongfu
    Zeng, Zhen
    TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2021, 20 (01) : 1 - 9
12345