New advances in countercurrent chromatography and centrifugal partition chromatography: focus on coupling strategy

被引：0
|
作者：
Thomas Michel
Emilie Destandau
Claire Elfakir
机构：
[1] Institut de Chimie Organique et Analytique UMR 7311,Université d’Orléans‐CNRS
来源：
Analytical and Bioanalytical Chemistry | 2014年 / 406卷
关键词：
HSCCC; CPC; MS; On-line and off-line coupling; Extraction; Purification; Natural products;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Countercurrent chromatography (CCC) is an attractive separation method because the analytes are partitioned between two immiscible liquid phases avoiding problems related to solid stationary phase. In recent years, this technique has made great progress in separation power and detection potential. This review describes coupling strategies involving high speed CCC (HSCCC) or centrifugal partition chromatography (CPC). It includes on-line extraction–isolation, hyphenation with mass spectrometry (MS) and nuclear magnetic resonance (NMR) detectors, multidimensional CCC (MDCCC), two-dimensional CCC (2D-CCC), on-line coupling with liquid chromatography (LC), and biological tests, and innovative off-line developments. The basic principles of each method are presented and applications are summarized.
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页码：957 / 969
页数：12
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