Neurological manifestations of SARS-CoV-2: complexity, mechanism and associated disorders

被引:0
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作者
Kritika Tyagi
Prachi Rai
Anuj Gautam
Harjeet Kaur
Sumeet Kapoor
Ashish Suttee
Pradeep Kumar Jaiswal
Akanksha Sharma
Gurpal Singh
Ravi Pratap Barnwal
机构
[1] Panjab University,Department of Biophysics
[2] Indian Institute of Technology,Centre for Biomedical Engineering
[3] Lovely Professional University,School of Pharmaceutical Sciences
[4] Texas A & M University,Department of Biochemistry and Biophysics
[5] University Institute of Pharmaceutical Sciences,undefined
[6] Panjab University,undefined
关键词
SARS-CoV-2; COVID; Blood–brain barrier; Central nervous system; Neuroinvasion; ACE-2; Cerebrovascular disease;
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摘要
SARS-CoV-2, causative agent of COVID-19 which halted the world, has neurological implications.Viruses infiltrate the nervous system by vesicle-mediated transport, transcytosis, molecular envelope technology, neurotropism, and direct invasion.Olfactory invasion by SARS-CoV-2 and ACE2 expression in the brain lead to an increase in lung infection cases.Encephalitis, Multiple Sclerosis, Ischemic Stroke etc. are some of the diseases which are a result of neuroinvasion by SARS-CoV-2.
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