New concepts in the design of drug-eluting coronary stents

New-generation drug-eluting stents (DES) utilize various drugs, polymers, and scaffold technologies, which have improved the safety of these stents in comparison with first-generation DES. Clinicians now have a variety of stents to choose from, and the choice can be tailored to the individual patient. Garg and colleagues present the concepts and rationale behind these new stent designs, and introduce some of the clinical data that support their use. In this Review, they aim to provide an update for general and interventional cardiologists who treat patients undergoing percutaneous coronary intervention.