Design of a ridge filter for spread-out Bragg-peak production in a pulsed 100-MeV proton beam

被引:0
|
作者
Myung-Hwan Jung
Se-Jin Ra
Kye-Ryung Kim
机构
来源
关键词
Energy modulator; 100-MeV Proton beam;
D O I
暂无
中图分类号
学科分类号
摘要
We designed a ridge-filter-type modulator suitable for 100-MeV pulsed proton beam modulation. It can be applied to a variety of experiments, such as in medical technology and space technology proton beam modulation from the surface to an 8-cm depth. We also designed a 2-cm spread-out Bragg peak for cancer research using a small experimental animal orthotopic tumor model. The minimum thickness of the range modulator is specified as 2 mm for the mechanical support, and the maximum thickness in the 8-cm and 2-cm SOBP are specified as 40 mm and 12 mm, respectively. The ridge interval and the drift distance are 8 mm and 30 cm, respectively. The design was carried out using the Stopping and Range of Ions in Matter and the Monte Carlo N-particle Extended codes. The results show that the two-dimensional dose distributions of the two range modulators are uniform.
引用
收藏
页码:1441 / 1445
页数:4
相关论文
共 50 条
  • [41] Semianalytical tool for spread-out Bragg peak optimization in an active energy-modulation proton therapy linac
    Ronsivalle, C.
    Nichelatti, E.
    Picardi, L.
    Montereali, R. M.
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2021, 988
  • [42] Feasibility Study of Quality Assurance of Proton Range Compensator Using the Proximal Side of Spread-Out Bragg Peak
    Jin, H.
    Ahmad, S.
    MEDICAL PHYSICS, 2017, 44 (06)
  • [43] Effect of 5-fluorouracil on cellular response to proton beam in esophageal cancer cell lines according to the position of spread-out Bragg peak
    Hojo, Hidehiro
    Dohmae, Takeshi
    Hotta, Kenji
    Kageyama, Shun-Ichiro
    Baba, Hiromi
    Kohno, Ryosuke
    Motegi, Atsushi
    Tsuchihara, Katsuya
    Akimoto, Tetsuo
    ACTA ONCOLOGICA, 2019, 58 (04) : 475 - 482
  • [44] Spread-out Bragg peak proton FLASH irradiation using a clinical synchrocyclotron: Proof of concept and ion chamber characterization
    Darafsheh, Arash
    Hao, Yao
    Zhao, Xiandong
    Zwart, Townsend
    Wagner, Miles
    Evans, Tucker
    Reynoso, Francisco
    Zhao, Tianyu
    MEDICAL PHYSICS, 2021, : 4472 - 4484
  • [45] Macrospot Filter for Generating Spread-out Bragg Peaks (SOBP) from Single-Energy Proton Beams
    Yi, B. Y.
    Mossahebi, S.
    Biswal, N. C.
    Polf, J. C.
    MEDICAL PHYSICS, 2024, 51 (10) : 7685 - 7685
  • [46] In vitro modified microdosimetric kinetic model-based predictions for B14-150 cells survival in 450 MeV/u carbon ion beam with aluminum ridge filter for biologically optimized spread-out Bragg peak
    Solovev, Aleksei
    Troshina, Marina
    Pikalov, Vladimir
    Saburov, Vyacheslav
    Chernukha, Aleksandr
    Moiseev, Aleksandr
    Koryakina, Ekaterina
    Potetnya, Vladimir
    Koryakin, Sergey
    Soldatov, Aleksandr
    Kaprin, Andrey
    BIOMEDICAL PHYSICS & ENGINEERING EXPRESS, 2022, 8 (03)
  • [47] Design of 100-MeV proton beam spreading scheme with double-ring double scattering method
    Han Jin-Hua
    Guo Gang
    Liu Jian-Cheng
    Sui Li
    Kong Fu-Quan
    Xiao Shu-Yan
    Qin Ying-Can
    Zhang Yan-Wen
    ACTA PHYSICA SINICA, 2019, 68 (05)
  • [48] The impact of DNA double-strand break repair pathways throughout the carbon ion spread-out Bragg peak beam
    Buglewicz, Dylan J.
    Buglewicz, Jessica K. F.
    Hirakawa, Hirokazu
    Kato, Takamitsu A.
    Cuihua, Liu
    Fang, Yaqun
    Kusumoto, Tamon
    Fujimori, Akira
    Sai, Sei
    CANCER SCIENCE, 2023, 114 (12) : 4548 - 4557
  • [49] Correcting Spread-Out Bragg Peak Slope Using Time-Resolved Monte Carlo Simulations and Beam Current Modulation
    Hill, P.
    Klein, E.
    Bloch, C.
    MEDICAL PHYSICS, 2012, 39 (06) : 3871 - 3872
  • [50] Improving the Accuracy of Monte Carlo Spread-Out Bragg Peak Treatment Head Models Using Beam Current Modulation Optimization
    Bednarz, B.
    Lu, H.
    Engelsman, M.
    Paganetti, H.
    MEDICAL PHYSICS, 2010, 37 (06)