Synthesis, evaluation, in silico ADMET screening, HYDE scoring, and molecular docking studies of synthesized 1-trityl-substituted 1H-imidazoles

被引：0
|
作者：
Hezha O. Rasul
机构：
[1] Charmo University,Department of Pharmaceutical Chemistry, College of Science
来源：
Journal of the Iranian Chemical Society | 2023年 / 20卷
关键词：
Synthesis; Grignard reaction; HYDE; Azole antifungals; Molecular docking; ADMET;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：2905 / 2916
页数：11
相关论文
共 50 条
  • [21] Synthesis, antibacterial evaluation, in silico ADMET and molecular docking studies of new N-acylhydrazone derivatives from acridone
    Aarjane, Mohammed
    Aouidate, Adnane
    Slassi, Siham
    Amine, Amina
    ARABIAN JOURNAL OF CHEMISTRY, 2020, 13 (07) : 6236 - 6245
  • [22] Synthesis and Anti-Candida Potential of Certain Novel 1-[(3-Substituted-3-phenyl)propyl]-1H-imidazoles
    Aboul-Enein, Mohamed Nabil
    El-Azzouny, Aida Abd El-Sattar
    Attia, Mohamed Ibrahim
    Saleh, Ola Ahmed
    Kansoh, Amany Lotfy
    ARCHIV DER PHARMAZIE, 2011, 344 (12) : 794 - 801
  • [23] Crystal structure and molecular docking studies of 1,2,4,5-tetraaryl substituted imidazoles
    Sharma, Devinder Kumar
    Jayashree, Avvadukkam
    Narayana, Badiadka
    Sarojini, Balladka Kunhana
    Ravikumar, Chandrasekaran
    Murugavel, Saminathan
    Anthal, Sumati
    Kant, Rajni
    HETEROCYCLIC COMMUNICATIONS, 2018, 24 (04) : 205 - 210
  • [24] Synthesis of new thiourea derivatives and metal complexes: Thermal behavior, biological evaluation, in silico ADMET profiling and molecular docking studies
    Yesilkaynak, Tuncay
    oezkoemec, Fatma Nur
    cesme, Mustafa
    Demirdoegen, Ruken Esra
    Kutlu, Emine
    Kutlu, Hatice Mehtap
    Emen, Fatih Mehmet
    JOURNAL OF MOLECULAR STRUCTURE, 2022, 1269
  • [25] SYNTHESIS AND OPTICAL STUDIES OF 2,4,5-TRI[2-(ARYL)-ETHENYL]-1H-IMIDAZOLES
    Babar, Rabia
    Munawar, Munawar Ali
    HETEROCYCLES, 2019, 98 (03) : 429 - 436
  • [26] Catalytic multicomponent synthesis, biological evaluation, molecular docking and in silico ADMET studies of some novel 3-alkyl indoles
    Ramarajan, Rajalakshmi
    Ramalingam, Arulraj
    Duraisamy, Chinnaraja
    Sambandam, Sivakumar
    Issaoui, Noureddine
    Al-Dossary, Omar M.
    Bousiakoug, Leda G.
    JOURNAL OF KING SAUD UNIVERSITY SCIENCE, 2023, 35 (02)
  • [27] Design and Synthesis of New Quinoxaline-Oxazole-Morpholino Conjugates; Evaluation of Anticancer Activity and In Silico Molecular Docking and ADMET Studies
    Bonakolluru, Yellaiah
    Marupati, Siddhartha
    Kandala, Satyanarayana
    Dasari, Gouthami
    Manchal, Ravinder
    Bandari, Srinivas
    CHEMISTRYSELECT, 2025, 10 (01):
  • [28] Facile synthesis of fully substituted 1H-imidazoles from oxime esters via dual photoredox/copper catalyzed multicomponent reactions
    Cao, Shujun
    Ma, Chongchong
    Teng, Xinjie
    Chen, Rongshun
    Li, Yun
    Yuan, Weidong
    Zhu, Yingguang
    ORGANIC CHEMISTRY FRONTIERS, 2022, 9 (24) : 6817 - 6825
  • [29] Studies on isocyanides and related compounds. Synthesis of 1-aryl-2-(tosylamino)-1H-imidazoles, a novel class of imidazole derivatives
    Bossio, R
    Marcaccini, S
    Pepino, R
    JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (06): : 2202 - 2203
  • [30] Synthesis, Molecular Docking Studies and In Silico ADMET Screening of New Heterocycles Linked Thiazole Conjugates as Potent Anti-Hepatic Cancer Agents
    Rashdan, Huda R. M.
    El-Naggar, Mohamed
    Abdelmonsef, Aboubakr H.
    MOLECULES, 2021, 26 (06):
12345