Enhanced oxidative stress in hypertrophic cardiomyopathy

被引：0
|
作者：
Paweł P. Dimitrow
Anetta Undas
Paweł Wołkow
Wiesława Tracz
Jacek S. Dubiel
机构：
[1] Jagiellonian University,2nd Department of Cardiology, Collegium Medicum
[2] Collegium Medicum Jagiellonian University,Department of Cardiac and Vascular Disease
[3] Jagiellonian University,Department of Pharmacology, Collegium Medicum
来源：
Pharmacological Reports | 2009年 / 61卷
关键词：
hypertrophic cardiomyopathy; oxidative stress;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Elevated plasma levels of inflammation and endothelial dysfunction markers have been reported in patients with hypertrophic car diomyopathy (HCM). The aim of the current study was to determine whether HCM is associated with enhanced oxidative stress. We enrolled 54 HCM patients with sinus rhythm, including 21 subjects with a left ventricular outflow tract (LVOT) obstruction (gra dient > 30 mmHg), and 54 age- and sex-matched controls without cardiovascular diseases. Serum levels of 8-isoprostaglandin F2a (8-iso-PGF2α), a stable marker of oxidative stress, were determined.
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页码：491 / 495
页数：4
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