Effect of peptide pro-gly-pro on stress-induced behavioral changes in rats

被引：0
|
作者：
Kopylova G.N. [1 ]
Badmaeva S.E. [1 ]
Levitskaya N.G. [1 ]
Samonina G.E. [1 ]
Umarova B.A. [1 ]
Guseva A.A. [1 ]
机构：
[1] Dept. of Human/Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State Univ., Moscow
来源：
Bulletin of Experimental Biology and Medicine | 2004年 / 138卷 / 1期
关键词：
Behavior; Regulatory peptides; Stress;
D O I：
10.1023/B:BEBM.0000046923.37415.4e
中图分类号：
学科分类号：
摘要：
Tripeptide PGP in a dose of 1 mg/kg had a correcting effect on behavioral disorders in rats induced by stress exposure (forced swimming). PGP prevented the increase in anxiety and decrease in orientation and exploratory activity. Our results suggest that the effect of this peptide is realized via central nervous structures involved in organism's response to stress factors. © 2004 Springer Science + Business Media, Inc.
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页码：5 / 7
页数：2
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