Effect of peptide pro-gly-pro on stress-induced behavioral changes in rats

被引：0
|
作者：
Kopylova G.N. [1 ]
Badmaeva S.E. [1 ]
Levitskaya N.G. [1 ]
Samonina G.E. [1 ]
Umarova B.A. [1 ]
Guseva A.A. [1 ]
机构：
[1] Dept. of Human/Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State Univ., Moscow
来源：
Bulletin of Experimental Biology and Medicine | 2004年 / 138卷 / 1期
关键词：
Behavior; Regulatory peptides; Stress;
D O I：
10.1023/B:BEBM.0000046923.37415.4e
中图分类号：
学科分类号：
摘要：
Tripeptide PGP in a dose of 1 mg/kg had a correcting effect on behavioral disorders in rats induced by stress exposure (forced swimming). PGP prevented the increase in anxiety and decrease in orientation and exploratory activity. Our results suggest that the effect of this peptide is realized via central nervous structures involved in organism's response to stress factors. © 2004 Springer Science + Business Media, Inc.
引用
收藏
页码：5 / 7
页数：2
相关论文
共 50 条
  • [1] Effect of peptide pro-gly-pro on stress-induced behavioral changes in rats
    Kopylova, GN
    Badmaeva, SE
    Levitskaya, NG
    Samonina, GE
    Umarova, BA
    Guseva, AA
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2004, 138 (01) : 5 - 7
  • [2] Effect of peptide Pro-Gly-Pro on stress-induced behavioral changes in rats
    G. N. Kopylova
    S. E. Badmaeva
    N. G. Levitskaya
    G. E. Samonina
    B. A. Umarova
    A. A. Guseva
    Bulletin of Experimental Biology and Medicine, 2004, 138 (7) : 5 - 7
  • [3] Effect of the Pro-Gly-Pro peptide on resistance of rats to acute hypobaric hypoxia and posthypoxic behavioral disorders
    S. E. Edeeva
    K. E. Baglikova
    G. N. Kopylova
    G. E. Samonina
    B. A. Umarova
    Z. V. Bakaeva
    R. D. Platonova
    Moscow University Biological Sciences Bulletin, 2008, 63 (4) : 145 - 149
  • [4] Effect of the PRO-GLY-PRO peptide on hemostasis and lipid metabolism in rats with hypercholesterolemia
    Andreeva L.A.
    Myasoedov N.F.
    Lyapina L.A.
    Grigor'eva M.E.
    Obergan T.Y.
    Shubina T.A.
    Doklady Biological Sciences, 2013, 453 (1) : 333 - 335
  • [5] Changes in hemostatic parameters after intranasal administration of peptide Pro-Gly-Pro
    Lyapina, L. A.
    Pastorova, V. E.
    Obergan, T. Yu.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2007, 144 (04) : 491 - 493
  • [6] Changes in hemostatic parameters after intranasal administration of peptide Pro-Gly-Pro
    L. A. Lyapina
    V. E. Pastorova
    T. Yu. Obergan
    Bulletin of Experimental Biology and Medicine, 2007, 144 : 491 - 493
  • [7] A Novel Fluorometric Method for the Selective Determination of Pro-Gly and Pro-Gly-Pro
    Yasmin, Hasina
    Rahman, Mohammed Shafikur
    Shibata, Takayuki
    Kabashima, Tsutomu
    Kai, Masaaki
    INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2014, 20 (04) : 441 - 446
  • [8] A Novel Fluorometric Method for the Selective Determination of Pro-Gly and Pro-Gly-Pro
    Hasina Yasmin
    Mohammed Shafikur Rahman
    Takayuki Shibata
    Tsutomu Kabashima
    Masaaki Kai
    International Journal of Peptide Research and Therapeutics, 2014, 20 : 441 - 446
  • [9] Effects of Pro-Gly-Pro Tripeptide on the Dopamine System
    V. K. Meshavkin
    E. Yu. Batishcheva
    N. V. Kost
    O. Yu. Sokolov
    A. V. Trufanova
    G. E. Samonina
    Bulletin of Experimental Biology and Medicine, 2011, 151 : 429 - 431
  • [10] The Pro-Gly-Pro tripeptide and homeostasis of the gastric mucosa
    Samonina, G. E.
    Kopylova, G. N.
    Umarova, B. A.
    NEUROCHEMICAL JOURNAL, 2008, 2 (1-2) : 111 - 114
12345