The protein botulinum neurotoxin A (BoNT/A) is one of seven distinct neurotoxins produced by Clostridium botulinum. BoNT/A blocks cholinergic synapses with an extremely high specificity and potency. Appropriately purified and diluted, BoNT/A serves as a reliable and well tolerated drug that is applied by local injection.
机构:
Univ Calif Los Angeles, David Geffen Sch Med, Dept Dermatol, Beverly Hills, CA 90210 USAUniv Calif Los Angeles, David Geffen Sch Med, Dept Dermatol, Beverly Hills, CA 90210 USA